Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …

The biogenesis, folding, and structure of α-helical membrane proteins (MPs) are important to
understand because they underlie virtually all physiological processes in cells including key …

▪ Abstract Stably folded membrane proteins reside in a free energy minimum determined by
the interactions of the peptide chains with each other, the lipid bilayer hydrocarbon core, the …

• Introduction• Membrane lipid composition• Membrane lipid structure• Membrane lipid
organization‐Why so many different lipids?‐Lipid mixing and demixing‐Lateral pressure …

The β-barrel membrane protein is found in the outer membranes of bacteria, mitochondria
and chloroplasts. Approximately 2–3% of the genes in Gram-negative bacterial genomes …

We recently described 10 peptides selected from a 16 384-member combinatorial library
based on their ability to permeabilize synthetic lipid vesicles in vitro. These peptides did not …

This review is focused on peptide molecules which exhibit a limited solubility in the aqueous
phase and bind to the lipid membrane from the aqueous medium. Surface adsorption …

Membranes have a potent ability to promote secondary structure formation in a wide range
of membrane-active peptides, believed to be due to a reduction through hydrogen bonding …

The conversion of soluble protein into β-sheet-rich amyloid fibers is the hallmark of a
number of serious diseases. Precursors for many of these systems (eg, Aβ from Alzheimer's …

Although the problem of the folding of soluble proteins continues to resist solution, we at
least have a strong understanding of the general thermodynamic principles1, 2 and have …