Rationale Allergic diseases are an increasing public health concern, and early life
environment is critical to immune development. Maternal diet during pregnancy has been …

Importance Neural tube defects are among the most common congenital anomalies in the
United States. Periconceptional folic acid supplementation is a primary care–relevant …

Atopic dermatitis (AD) is a chronic inflammatory skin disease caused by a combination of
genetic and environmental factors. Genetic evidences depict a complex network comprising …

Maternal exposure to dietary factors during pregnancy can influence embryonic
development and may modulate the phenotype of offspring through epigenetic …

Epigenetics of asthma and allergic disease is a field that has expanded greatly in the last
decade. Previously thought only in terms of cell differentiation, it is now evident the …

The clinical significance of periconceptional folic acid supplementation (FAS) in the
prevention of neonatal neural tube defects (NTDs) has been recognized for decades …

Asthma is heritable, influenced by the environment, and modified by in utero exposures and
aging; all of these features are also common to epigenetic regulation. Furthermore, the …

Childhood asthma is an umbrella of multifactorial diseases with similar clinical features such
as mast cell and eosinophil infiltration causing airway hyper responsiveness, inflammation …

Background After an era of only considering the allergenic properties of the infant diet and
allergy outcomes, emerging data suggest that the overall composition of the infant diet might …

The research field of fetal programming has developed tremendously over the years and
increasing knowledge suggests that both maternal and paternal unbalanced diet can have …