The SWI/SNF complex and cancer
D Reisman, S Glaros, EA Thompson - Oncogene, 2009 - nature.com
The mammalian SWI/SNF complexes mediate ATP-dependent chromatin remodeling
processes that are critical for differentiation and proliferation. Not surprisingly, loss of …
processes that are critical for differentiation and proliferation. Not surprisingly, loss of …
Oncogenic roles of SMARCB 1/INI 1 and its deficient tumors
K Kohashi, Y Oda - Cancer science, 2017 - Wiley Online Library
SMARCB 1/INI 1 is one of the core subunit proteins of the ATP‐dependent SWI/SNF
chromatin remodeling complex, and is identified as a potent and bona fide tumor …
chromatin remodeling complex, and is identified as a potent and bona fide tumor …
Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes
A Alpsoy, EC Dykhuizen - Journal of Biological Chemistry, 2018 - ASBMB
The mammalian SWI/SNF chromatin remodeling complex is a heterogeneous collection of
related protein complexes required for gene regulation and genome integrity. It contains a …
related protein complexes required for gene regulation and genome integrity. It contains a …
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
I Versteege, N Sévenet, J Lange, MF Rousseau-Merck… - Nature, 1998 - nature.com
Malignant rhabdoid tumours (MRTs) are extremely aggressive cancers of early childhood.
They can occur in various locations, mainly the kidney, brain and soft tissues,. Cytogenetic …
They can occur in various locations, mainly the kidney, brain and soft tissues,. Cytogenetic …
[HTML][HTML] HIV reproducibly establishes a latent infection after acute infection of T cells in vitro
The presence of latent reservoirs has prevented the eradication of human immunodeficiency
virus (HIV) from infected patients successfully treated with anti‐retroviral therapy. The …
virus (HIV) from infected patients successfully treated with anti‐retroviral therapy. The …
Germ-Line and Acquired Mutations of INI1 in Atypical Teratoid and Rhabdoid Tumors
JA Biegel, JY Zhou, LB Rorke, C Stenstrom… - Cancer research, 1999 - AACR
We examined 18 atypical teratoid and rhabdoid tumors of the brain and 7 renal and 4
extrarenal rhabdoid tumors for mutations in the candidate rhabdoid tumor suppressor gene …
extrarenal rhabdoid tumors for mutations in the candidate rhabdoid tumor suppressor gene …
Purification and biochemical heterogeneity of the mammalian SWI‐SNF complex.
We have purified distinct complexes of nine to 12 proteins [referred to as BRG1‐associated
factors (BAFs)] from several mammalian cell lines using an antibody to the SWI2‐SNF2 …
factors (BAFs)] from several mammalian cell lines using an antibody to the SWI2‐SNF2 …
HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells
P Cherepanov, G Maertens, P Proost… - Journal of Biological …, 2003 - ASBMB
We studied human immunodeficiency virus, type 1 (HIV-1) integrase (IN) complexes derived
from nuclei of human cells stably expressing the viral protein from a synthetic gene. We …
from nuclei of human cells stably expressing the viral protein from a synthetic gene. We …
Diversity and specialization of mammalian SWI/SNF complexes.
The SWI/SNF complex in yeast facilitates the function of transcriptional activators by
opposing chromatin-dependent repression of transcription. We demonstrate that in …
opposing chromatin-dependent repression of transcription. We demonstrate that in …
Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling
Lymphocyte activation is accompanied by visible changes in chromatin structure. We find
that antigen receptor signaling induces the rapid association of the BAF complex with …
that antigen receptor signaling induces the rapid association of the BAF complex with …