Revisiting inorganic nanoparticles as promising therapeutic agents: A paradigm shift in oncological theranostics

MA Khan, D Singh, A Ahmad, HR Siddique - European Journal of …, 2021 - Elsevier
Cancer remains a global health problem largely due to a lack of effective therapies. Major
cancer management strategies include chemotherapy, surgical resection, and radiation …

Unveiling the therapeutic promise of natural products in alleviating drug‐induced liver injury: Present advancements and future prospects

D Singh, MA Khan, HR Siddique - Phytotherapy Research, 2024 - Wiley Online Library
Drug‐induced liver injury (DILI) refers to adverse reactions to small chemical compounds,
biological agents, and medical products. These reactions can manifest as acute or chronic …

Accentuating CircRNA-miRNA-transcription factors axis: a conundrum in cancer research

D Singh, P Kesharwani, NA Alhakamy… - Frontiers in …, 2022 - frontiersin.org
Circular RNAs (circRNAs) are the newly uncovered class of non-coding RNAs being
cognized as profound regulators of gene expression in developmental and disease biology …

Therapeutic implications of probiotics in microbiota dysbiosis: A special reference to the liver and oral cancers

D Singh, MA Khan, HR Siddique - Life Sciences, 2021 - Elsevier
The microbiota plays an important role in maintaining the body's homeostasis. Imbalance in
the microbiota is referred to as microbiota dysbiosis. Microbiota dysbiosis leads to pro …

Antiandrogen enzalutamide induced genetic, cellular, and hepatic damages: amelioration by triterpene Lupeol

MA Khan, D Singh, H Fatma, K Akhtar… - Drug and Chemical …, 2023 - Taylor & Francis
Androgen deprivation therapy is commonly used for the treatment of prostate cancer.
Enzalutamide is a next-generation androgen receptor inhibitor, initially approved to treat …

[HTML][HTML] Apigenin enhances sorafenib anti-tumour efficacy in hepatocellular carcinoma

D Singh, MA Khan, D Mishra, A Goel, MA Ansari… - Translational …, 2024 - Elsevier
Background The “one drug-one target” paradigm has various limitations affecting drug
efficacy, such as resistance profiles and adverse effects. Combinational therapies help …

Targeting metabolism with herbal therapy: A preventative approach toward cancer

D Singh, HR Siddique - Herbal Medicines, 2022 - Elsevier
The metabolic properties of cancer cells differ from normal cells. Cancer cells have atypical
metabolic processes such as dependence on glycolysis, increased fatty acid, and glutamine …

PLGA-based nanoparticles for the treatment of inflammatory diseases

D Singh, MA Khan, HR Siddique - Poly (lactic-co-glycolic acid)(PLGA) …, 2023 - Elsevier
Poly (lactic-co-glycolic acid)(PLGA) is the most widely used polymer approved by the United
States FDA for diagnostics, drug delivery, and other applications due to its biodegradability …

The Multi-Targeting Efficacy and Therapeutic Effects of Ayurveda and Chinese Medicine: An Integrated Approach for Cancer Treatment and Management

MA Khan, HR Siddique - Ethnic Knowledge and Perspectives of …, 2023 - taylorfrancis.com
Herbal-based traditional medicines have a long history of therapeutic application throughout
the world. Ayurveda and Chinese herbs have been traditionally used as indigenous …

[引用][C] Revisiting epigenetic regulation in cancer: Evolving trends and translational implications

MA Khan, D Mishra, R Kumar, HR Siddique - 2024 - Elsevier