Genetically Engineered‐Cell‐Membrane Nanovesicles for Cancer Immunotherapy
Q Cheng, Y Kang, B Yao, J Dong, Y Zhu… - Advanced …, 2023 - Wiley Online Library
The advent of immunotherapy has marked a new era in cancer treatment, offering significant
clinical benefits. Cell membrane as drug delivery materials has played a crucial role in …
clinical benefits. Cell membrane as drug delivery materials has played a crucial role in …
Effects of glioblastoma-derived extracellular vesicles on the functions of immune cells
OE Musatova, YP Rubtsov - Frontiers in cell and developmental …, 2023 - frontiersin.org
Glioblastoma is the most aggressive variant of glioma, the tumor of glial origin which
accounts for 80% of brain tumors. Glioblastoma is characterized by astoundingly poor …
accounts for 80% of brain tumors. Glioblastoma is characterized by astoundingly poor …
Photothermal therapy with HER2-targeted silver nanoparticles leading to cancer remission
VO Shipunova, MM Belova, PA Kotelnikova… - Pharmaceutics, 2022 - mdpi.com
Nanoparticles exhibiting the localized surface plasmon resonance (LSPR) phenomenon are
promising tools for diagnostics and cancer treatment. Among widely used metal …
promising tools for diagnostics and cancer treatment. Among widely used metal …
Direct in vivo activation of T cells with nanosized immunofilaments inhibits tumor growth and metastasis
L Weiss, J Weiden, Y Dölen, EM Grad… - Acs Nano, 2023 - ACS Publications
Adoptive T cell therapy has successfully been implemented for the treatment of cancer.
Nevertheless, ex vivo expansion of T cells by artificial antigen-presenting cells (aAPCs) …
Nevertheless, ex vivo expansion of T cells by artificial antigen-presenting cells (aAPCs) …
Extracellular vesicles expressing CD19 antigen improve expansion and efficacy of CD19-targeted CAR-T cells
Y Zhang, T Ge, M Huang, Y Qin, T Liu… - International Journal …, 2023 - Taylor & Francis
Background CAR-T cell therapy is effective in the treatment of certain hematological
malignancies, and the expansion and functional persistence of CAR-T cells in vivo are …
malignancies, and the expansion and functional persistence of CAR-T cells in vivo are …
Genetically encoded self-assembling protein nanoparticles for the targeted delivery in vitro and in vivo
Targeted nanoparticles of different origins are considered as new-generation diagnostic and
therapeutic tools. However, there are no targeted drug formulations within the composition of …
therapeutic tools. However, there are no targeted drug formulations within the composition of …
Cell membrane-derived vesicle: A novel vehicle for cancer immunotherapy
As nano-sized materials prepared by isolating, disrupting and extruding cell membranes,
cellular vesicles are emerging as a novel vehicle for immunotherapeutic drugs to activate …
cellular vesicles are emerging as a novel vehicle for immunotherapeutic drugs to activate …
CAR-tropic extracellular vesicles carry tumor-associated antigens and modulate CAR T cell functionality
VM Ukrainskaya, OE Musatova, DV Volkov… - Scientific Reports, 2023 - nature.com
Tumor-derived extracellular vesicles (EVs) are active contributors in metastasis and
immunosuppression in tumor microenvironment. At least some of the EVs carry tumor …
immunosuppression in tumor microenvironment. At least some of the EVs carry tumor …
Advanced Materials and Delivery Systems for Enhancement of Chimeric Antigen Receptor Cells
T Li, R Luo, L Su, F Lv, L Mei, Y Yu - Small Methods, 2023 - Wiley Online Library
Chimeric antigen receptor (CAR) cell therapy is a great success and breakthrough in
immunotherapy. However, there are still lots of barriers to its wide use in clinical, including …
immunotherapy. However, there are still lots of barriers to its wide use in clinical, including …
Genetically engineered CD80–pMHC-harboring extracellular vesicles for antigen-specific CD4+ T-cell engagement
IA Ishina, IN Kurbatskaia, AE Mamedov… - … in Bioengineering and …, 2024 - frontiersin.org
The identification of low-frequency antigen-specific CD4+ T cells is crucial for effective
immunomonitoring across various diseases. However, this task still encounters experimental …
immunomonitoring across various diseases. However, this task still encounters experimental …