Metal nanoclusters: novel probes for diagnostic and therapeutic applications

Y Tao, M Li, J Ren, X Qu - Chemical Society Reviews, 2015 - pubs.rsc.org
Metal nanoclusters, composed of several to a few hundred metal atoms, have received
worldwide attention due to their extraordinary physical and chemical characteristics …

Stimuli-responsive chitosan as an advantageous platform for efficient delivery of bioactive agents

P Sabourian, M Tavakolian, H Yazdani… - Journal of Controlled …, 2020 - Elsevier
Despite a diverse range of active pharmaceutical agents currently at our disposal, high
morbidity rate diseases continue to pose a major health crisis globally. One of the important …

Cholinesterase-responsive supramolecular vesicle

DS Guo, K Wang, YX Wang, Y Liu - Journal of the American …, 2012 - ACS Publications
Enzyme-responsive, amphiphilic self-assembly represents one of the increasingly significant
topics in biomaterials research and finds feasible applications to the controlled release of …

The role of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in the development of esophageal cancer

M Groblewska, M Siewko, B Mroczko… - Folia histochemica et …, 2012 - journals.viamedica.pl
Esophageal cancer (EC) is one of the most aggressive malignant tumors of the
gastrointestinal tract. There are two distinct histological types of EC: esophageal squamous …

Nerves in gastrointestinal cancer: from mechanism to modulations

N Vaes, M Idris, W Boesmans, MM Alves… - Nature Reviews …, 2022 - nature.com
Maintenance of gastrointestinal health is challenging as it requires balancing multifaceted
processes within the highly complex and dynamic ecosystem of the gastrointestinal tract …

Transgenic mouse lines subdivide external segment of the globus pallidus (GPe) neurons and reveal distinct GPe output pathways

KJ Mastro, RS Bouchard, HAK Holt… - Journal of …, 2014 - Soc Neuroscience
Cell-type diversity in the brain enables the assembly of complex neural circuits, whose
organization and patterns of activity give rise to brain function. However, the identification of …

Epithelial-mesenchymal transition events during human embryonic stem cell differentiation

AM Eastham, H Spencer, F Soncin, S Ritson… - Cancer research, 2007 - AACR
Epithelial-mesenchymal transition (EMT) occurs during embryonic development and may
also be associated with the metastatic spread of epithelial tumors. During EMT, E-cadherin …

Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer

C Yu, Y Zhou, X Miao, P Xiong, W Tan, D Lin - Cancer research, 2004 - AACR
Abstract Matrix metalloproteinase-2 (MMP-2) plays important roles in cancer development
and aggression. Our previous studies revealed a strong association between the MMP-2 …

The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts …

T Okawa, CZ Michaylira, J Kalabis… - Genes & …, 2007 - genesdev.cshlp.org
Esophageal cancer is a prototypic squamous cell cancer that carries a poor prognosis,
primarily due to presentation at advanced stages. We used human esophageal epithelial …

[HTML][HTML] CCL3–CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways

T Kodama, Y Koma, N Arai, A Kido, N Urakawa… - Laboratory …, 2020 - Elsevier
Tumor-associated macrophages (TAMs) contribute to the progression and mortality of
various malignancies. We reported that high numbers of infiltrating TAMs were significantly …