Large granular lymphocyte (LGL) leukemia has been recognized by the World Health
Organization classifications amongst mature T-cell and natural killer (NK) cell neoplasms …

Large granular lymphocyte (LGL) leukemia has been recognized in the World Health
Organization classifications among mature T cell and natural killer cell neoplasms and is …

Distinguishing chronic lymphoproliferative disorders of NK cells (CLPD-NK) from reactive
NK-cell expansion is challenging. We assessed the value of killer immunoglobulin-like …

Cytotoxicity and consequent cell death pathways are a critical component of the immune
response to infection, disease or injury. While numerous examples of inflammation causing …

Large granular lymphocyte leukemia (LGLL) is a chronic proliferation of clonal cytotoxic
lymphocytes, usually presenting with cytopenias and yet lacking a specific therapy. The …

Simple Summary STAT3 and STAT5B mutations have been identified in a subset of T and
NK large granular lymphocytic leukemia (T/NK-LGLL). The aim of our study was to evaluate …

Large granular lymphocytic leukemia (LGLL) is a rare hematological malignancy that arises
from cytotoxic T lymphocytes (T‐LGLL) in 85% of cases and natural killer (NK) cells in the …

Tγδ large granular lymphocyte leukemia (LGLL) is a rare variant of T-cell LGLL (T-LGLL) that
has been less investigated as compared with the more frequent Tαβ LGLL, particularly in …

Abstract Large Granular Lymphocyte (LGL) Leukemia is a rare, heterogeneous even more
that once thought, chronic lymphoproliferative disorder characterized by the clonal …

Aggressive natural killer cell leukemia (ANKL) is a systemic NK-cell neoplasm, almost
always associated with Epstein-Barr virus (EBV). Rare cases of EBV-negative ANKL have …