1, 1, 1, 3, 3, 3-Hexafluoroisopropanol (HFIP) is a polar, strongly hydrogen bond-donating
solvent that has found numerous uses in organic synthesis due to its ability to stabilize ionic …

Abstract Transition-metal-catalysed, non-enzymatic transformations of C–H and C= C bonds
to C–N bonds through nitrene transfer (NT) are powerful synthetic tools to prepare valuable …

Intramolecular cyclization of nitrogen-containing molecules onto pendant alkenes is an
efficient strategy for the construction of N-heterocycles, which are of paramount importance …

Abstract Selective three‐component 1, 2‐diamination of 1, 3‐dienes with concurrent
introduction of two orthogonally protected amino groups remains unknown despite its …

Rapid and efficient access to structurally diverse β-fluoroalkylamines is in high demand, with
their wide presence and great importance in medicinal chemistry and drug development …

A ligand‐controlled system that enables regioselective trifluoromethylcyanation of 1, 3‐
enynes has been identified, which provides access to a variety of CF3‐containing tri‐and …

Electrophilic aminating reagents have seen a renaissance in recent years as effective
nitrogen sources for the synthesis of unprotected amino functionalities. Based on their …

Herein, we study the mechanism of iron-catalyzed direct synthesis of unprotected
aminoethers from olefins by a hydroxyl amine derived reagent using a wide range of …

Potassium fluoride (KF) is an ideal reagent for fluorination because it is safe, easy to handle
and low-cost. However, poor solubility in organic solvents coupled with limited strategies to …

The stereoselective synthesis of syn-β-fluoroaziridine building blocks via chiral aryl iodide-
catalyzed fluorination of allylic amines is reported. The method employs HF–pyridine as a …