Autoimmune pre-disease

K Bieber, JE Hundt, X Yu, M Ehlers, F Petersen… - Autoimmunity …, 2023 - Elsevier
Approximately 5% of the world-wide population is affected by autoimmune diseases.
Overall, autoimmune diseases are still difficult to treat, impose a high burden on patients …

[HTML][HTML] Epidermolysis bullosa acquisita: the 2019 update

H Koga, C Prost-Squarcioni, H Iwata… - Frontiers in …, 2019 - frontiersin.org
Epidermolysis bullosa acquisita (EBA) is an orphan autoimmune disease. Patients with EBA
suffer from chronic inflammation as well as blistering and scarring of the skin and mucous …

[HTML][HTML] Humoral epitope spreading in autoimmune bullous diseases

D Didona, G Di Zenzo - Frontiers in immunology, 2018 - frontiersin.org
Autoimmune blistering diseases are characterized by autoantibodies against structural
adhesion proteins of the skin and mucous membranes. Extensive characterization of their …

Clinical features and diagnosis of epidermolysis bullosa acquisita

A Vorobyev, RJ Ludwig, E Schmidt - Expert review of clinical …, 2017 - Taylor & Francis
Introduction: Epidermolysis bullosa acquisita (EBA) is a rare autoimmune blistering disease
of skin and mucous membranes. EBA is caused by autoantibodies against type VII collagen …

[HTML][HTML] Epidermolysis bullosa acquisita: from pathophysiology to novel therapeutic options

M Kasperkiewicz, CD Sadik, K Bieber… - Journal of Investigative …, 2016 - Elsevier
Epidermolysis bullosa acquisita (EBA) is a prototypic organ-specific autoimmune disease
induced by autoantibodies to type VII collagen causing mucocutaneous blisters. In the …

Clinical presentation, pathogenesis, diagnosis, and treatment of epidermolysis bullosa acquisita

RJ Ludwig - International Scholarly Research Notices, 2013 - Wiley Online Library
Epidermolysis bullosa acquisita (EBA) is a chronic mucocutaneous autoimmune skin
blistering disease. The pathogenic relevance of autoantibodies targeting type VII collagen …

Impact of serum cytokine levels on EEG-measured arousal regulation in patients with major depressive disorder and healthy controls

FM Schmidt, A Pschiebl, C Sander, KC Kirkby… - …, 2016 - karger.com
Background: In major depressive disorder (MDD), findings include hyperstable regulation of
brain arousal measured by electroencephalography (EEG) vigilance analysis and …

[HTML][HTML] Black patients of African descent and HLA-DRB1* 15: 03 frequency overrepresented in epidermolysis bullosa acquisita

C Zumelzu, C Le Roux-Villet, P Loiseau… - Journal of investigative …, 2011 - Elsevier
Epidermolysis bullosa acquisita (EBA) is a rare autoimmune bullous disease (AIBD).
However, higher EBA incidence and predisposing genetic factor (s) involving an HLA …

The carbohydrate switch between pathogenic and immunosuppressive antigen‐specific antibodies

M Collin, M Ehlers - Experimental dermatology, 2013 - Wiley Online Library
IgG antibodies have one conserved N‐glycosylation site at Asn 297 in each of their constant
heavy chain regions. These Fc glycans influence the overall structure and pro‐or anti …

IL-10 mediates plasmacytosis-associated immunodeficiency by inhibiting complement-mediated neutrophil migration

U Kulkarni, CM Karsten, T Kohler… - Journal of Allergy and …, 2016 - Elsevier
Background Plasmacytosis (ie, an expansion of plasma cell populations to much greater
than the homeostatic level) occurs in the context of various immune disorders and plasma …