The latest developments in imaging of fibroblast activation protein
A Altmann, U Haberkorn, J Siveke - Journal of Nuclear Medicine, 2021 - Soc Nuclear Med
Fibroblast activation protein (FAP), a membrane-anchored peptidase, is highly expressed in
cancer-associated fibroblasts in more than 90% of epithelial tumors and contributes to …
cancer-associated fibroblasts in more than 90% of epithelial tumors and contributes to …
[HTML][HTML] Fibroblast activation protein-based theranostics in cancer research: a state-of-the-art review
In recent years, quinoline-based fibroblast activation protein (FAP) inhibitors (FAPI) have
shown promising results in the diagnosis of cancer and several other diseases, making them …
shown promising results in the diagnosis of cancer and several other diseases, making them …
Head-to-head intra-individual comparison of biodistribution and tumor uptake of 68Ga-FAPI and 18F-FDG PET/CT in cancer patients
FL Giesel, C Kratochwil, J Schlittenhardt… - European journal of …, 2021 - Springer
Purpose FAPI ligands (fibroblast activation protein inhibitor), a novel class of radiotracers for
PET/CT imaging, demonstrated in previous studies rapid and high tumor uptake. The …
PET/CT imaging, demonstrated in previous studies rapid and high tumor uptake. The …
FAP and FAPI-PET/CT in malignant and non-malignant diseases: a perfect symbiosis?
K Dendl, SA Koerber, C Kratochwil, J Cardinale… - Cancers, 2021 - mdpi.com
Simple Summary FAPI represents a novel class of radiotracers demonstrating promising
results in terms of a high uptake in concordance with low background noise in several …
results in terms of a high uptake in concordance with low background noise in several …
FAPI-PET/CT in cancer imaging: a potential novel molecule of the century
R Huang, Y Pu, S Huang, C Yang, F Yang, Y Pu… - Frontiers in …, 2022 - frontiersin.org
Fibroblast activation protein (FAP), a type II transmembrane serine protease, is highly
expressed in more than 90% of epithelial tumors and is closely associated with various …
expressed in more than 90% of epithelial tumors and is closely associated with various …
State-of-the-art of FAPI-PET imaging: a systematic review and meta-analysis
Introduction Fibroblast activation protein-α (FAPα) is overexpressed on cancer-associated
fibroblasts in approximately 90% of epithelial neoplasms, representing an appealing target …
fibroblasts in approximately 90% of epithelial neoplasms, representing an appealing target …
Clinical summary of fibroblast activation protein inhibitor-based radiopharmaceuticals: cancer and beyond
Fibroblast activation protein (FAP) is a type II membrane-bound glycoprotein which is
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …
overexpressed in cancer-associated fibroblasts and activated fibroblasts at wound …
Pitfalls and common findings in 68Ga-FAPI PET: a pictorial analysis
L Kessler, J Ferdinandus, N Hirmas… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Fibroblast activation protein inhibitor (FAPI) PET/CT is a new tool in the diagnostic workup of
cancer. With a growing volume of applications, pitfalls and common findings need to be …
cancer. With a growing volume of applications, pitfalls and common findings need to be …
[HTML][HTML] Fibroblast activation protein activates macrophages and promotes parenchymal liver inflammation and fibrosis
AT Yang, YO Kim, XZ Yan, H Abe, M Aslam… - Cellular and Molecular …, 2023 - Elsevier
Background & Aims Fibroblast activation protein (FAP) is expressed on activated fibroblast.
Its role in fibrosis and desmoplasia is controversial, and data on pharmacological FAP …
Its role in fibrosis and desmoplasia is controversial, and data on pharmacological FAP …
The potential utility of [68 Ga]Ga-DOTA-FAPI-04 as a novel broad-spectrum oncological and non-oncological imaging agent—comparison with [18F]FDG
L Lan, H Liu, Y Wang, J Deng, D Peng, Y Feng… - European journal of …, 2022 - Springer
Purpose This study aimed to compare the detection performance of [68 Ga] Ga-DOTA-FAPI-
04 and [18F] FDG PET/CT in the patients with various oncological and non-oncological …
04 and [18F] FDG PET/CT in the patients with various oncological and non-oncological …