This analysis examines the opioid crisis in the United States as a significant public health
challenge. It highlights the increasing prevalence of opioid misuse and overdose-related …

Background: A major part of the HEALing Communities Study (HCS), launched in 2019 to
address the growing opioid epidemic, is evaluating the study's intervention implementation …

Background Long‐term use of opioids does not result in significant clinical improvement and
has shown more adverse than beneficial effects in chronic pain conditions. When opioids …

Purpose: Opioid use disorder has caused significant morbidity and mortality resulting in
opioid prescribing limiting laws, such as State Bill 273 in West Virginia. The purpose of this …

Purpose: We aimed to help community stakeholders develop a shared understanding of the
opioid crisis through qualitative system dynamics (SD) modeling to inform local strategies for …

Background: Medication disposal programs have been promoted as one solution to the
opioid crisis, but uptake by community members has been minimal. Objectives: To clarify …

Background The OPTIMIZE trial is a multi-site, comparative effectiveness research (CER)
study that uses a Sequential Multiple Assessment Randomized Trial (SMART) designed to …

Background Promoting appropriate pharmacotherapy requires understanding the factors
that influence how clinicians prescribe medications. While prior work has focused on patient …

Background Prescription opioids were a major initial driver of the opioid crisis. States have
attempted to reduce overprescribing by enacting policies that limit opioid prescriptions, but …

Background: Several US states have introduced legislation to support the legitimate medical
use of opioids while limiting misuse and diversion. One concern which has been addressed …