Whole-genome sequencing surveillance and machine learning of the electronic health record for enhanced healthcare outbreak detection
Background Most hospitals use traditional infection prevention (IP) methods for outbreak
detection. We developed the Enhanced Detection System for Healthcare-Associated …
detection. We developed the Enhanced Detection System for Healthcare-Associated …
Whole-genome sequencing surveillance and machine learning for healthcare outbreak detection and investigation: a systematic review and summary
AJ Sundermann, J Chen, JK Miller… - Antimicrobial …, 2022 - cambridge.org
Background: Whole-genome sequencing (WGS) has traditionally been used in infection
prevention to confirm or refute the presence of an outbreak after it has occurred. Due to …
prevention to confirm or refute the presence of an outbreak after it has occurred. Due to …
Gastrointestinal endoscope contamination rates–elevators are not only to blame: a systematic review and meta-analysis
H Goyal, S Larsen, A Perisetti… - Endoscopy …, 2022 - thieme-connect.com
Background and study aims Duodenoscopes that are contaminated due to inadequate
reprocessing are well-documented. However, studies have demonstrated poor reprocessing …
reprocessing are well-documented. However, studies have demonstrated poor reprocessing …
Two Artificial Tears Outbreak-Associated Cases of Extensively Drug-Resistant Pseudomonas aeruginosa Detected Through Whole Genome Sequencing–Based …
AJ Sundermann, V Rangachar Srinivasa… - The Journal of …, 2024 - academic.oup.com
We describe 2 cases of extensively drug-resistant Pseudomonas aeruginosa infection
caused by a strain of public health concern, as it was recently associated with a nationwide …
caused by a strain of public health concern, as it was recently associated with a nationwide …
In host evolution of beta lactam resistance during active treatment for Pseudomonas aeruginosa bacteremia
N Spottiswoode, S Hao, E Sanchez-Guerrero… - Frontiers in Cellular …, 2023 - frontiersin.org
Multidrug-resistant (MDR) Pseudomonas aeruginosa has been declared a serious threat by
the United States Centers for Disease Control and Prevention. Here, we used whole …
the United States Centers for Disease Control and Prevention. Here, we used whole …
Genomic diversity of hospital-acquired infections revealed through prospective whole-genome sequencing-based surveillance
Healthcare-associated infections (HAIs) cause mortality, morbidity, and waste of health care
resources. HAIs are also an important driver of antimicrobial resistance, which is increasing …
resources. HAIs are also an important driver of antimicrobial resistance, which is increasing …
New Variants of Pseudomonas aeruginosa High-Risk Clone ST233 Associated with an Outbreak in a Mexican Paediatric Hospital
P Aguilar-Rodea, EL Estrada-Javier, V Jiménez-Rojas… - Microorganisms, 2022 - mdpi.com
Recent multidrug resistance in Pseudomonas aeruginosa has favoured the adaptation and
dissemination of worldwide high-risk strains. In June 2018, 15 P. aeruginosa strains isolated …
dissemination of worldwide high-risk strains. In June 2018, 15 P. aeruginosa strains isolated …
Innovative techniques for infection control and surveillance in hospital settings and long-term care facilities: a scoping review
Healthcare-associated infections (HAIs) pose significant challenges in healthcare systems,
with preventable surveillance playing a crucial role. Traditional surveillance, although …
with preventable surveillance playing a crucial role. Traditional surveillance, although …
The clinical and epidemiological impacts of whole genomic sequencing on bacterial and virological agents
S Timsit, L Armand-Lefèvre, J Le Goff… - Infectious Diseases Now, 2024 - Elsevier
Abstract Whole Genome Sequencing (WGS) is a molecular biology tool consisting in the
sequencing of the entire genome of a given organism. Due to its ability to provide the finest …
sequencing of the entire genome of a given organism. Due to its ability to provide the finest …
Sensitivity of National Healthcare Safety Network definitions to capture healthcare-associated transmission identified by whole-genome sequencing surveillance
AJ Sundermann, J Penzelik, A Ayres… - Infection Control & …, 2023 - cambridge.org
The National Healthcare Safety Network (NHSN) definitions are critical for standardizing
healthcare-associated infection surveillance in US healthcare facilities. However, their use …
healthcare-associated infection surveillance in US healthcare facilities. However, their use …