Abstract Purpose of Review Cryopreservation and its associated freezing and thawing
procedures–short “freeze-thawing”–are among the final steps in economically viable …

Cryopreservation is a process that preserves organelles, cells, tissues, or any other
biological constructs by cooling the samples to very low temperatures. The responses of …

Mesenchymal stem cells (MSCs), as the most common cell source for stem cell therapy, play
an important role in the modulation of innate and adaptive immune responses and have …

Extracellular vesicles (EVs) are small biological particles released into biofluids by every
cell. Based on their size, they are classified into small EVs (< 100 nm or< 200 nm) and …

Mesenchymal stem cells (MSCs) represent an invaluable asset for the field of cell therapy.
Human Bone marrow-derived MSCs (hBM-MSCs) are one of the most commonly used cell …

Mesenchymal stromal cells (MSCs) harbor great therapeutic potential for numerous
diseases. From early clinical trials, success and failure analysis, bench-to-bedside and back …

Cell-based medicine has made great advances in clinical diagnosis and therapy for various
refractory diseases, inducing a growing demand for cell preservation as support technology …

The three classical core technologies for the preservation of live mammalian biospecimens—
slow freezing, vitrification and hypothermic storage—limit the biomedical applications of …

In the unique supply chain of cellular therapies, preservation is important to keep the cell
product viable. Many factors in cryopreservation affect the outcome of a cell therapy:(i) …

Today, articular cartilage damage is a major health problem, affecting people of all ages.
The existing conventional articular cartilage repair techniques, such as autologous …