[HTML][HTML] Association between insulin resistance and the development of cardiovascular disease

V Ormazabal, S Nair, O Elfeky, C Aguayo… - Cardiovascular …, 2018 - Springer
For many years, cardiovascular disease (CVD) has been the leading cause of death around
the world. Often associated with CVD are comorbidities such as obesity, abnormal lipid …

Molecular and metabolic mechanisms of cardiac dysfunction in diabetes

CH Mandavia, AR Aroor, VG DeMarco, JR Sowers - Life sciences, 2013 - Elsevier
Diabetes mellitus type 2 (T2DM) is a widespread chronic medical condition with prevalence
bordering on the verge of an epidemic. It is of great concern that cardiovascular disease is …

Concurrent diabetes and heart failure: interplay and novel therapeutic approaches

QG Karwi, KL Ho, S Pherwani, EB Ketema… - Cardiovascular …, 2022 - academic.oup.com
Diabetes mellitus increases the risk of developing heart failure, and the co-existence of both
diseases worsens cardiovascular outcomes, hospitalization, and the progression of heart …

[HTML][HTML] Trimetazidine in practice: review of the clinical and experimental evidence

CA Dézsi - American journal of therapeutics, 2016 - journals.lww.com
All of the following traditional agents for the management of stable angina pectoris include
the symptomatic treatment with heart rate–lowering agents such as β-blockers or non …

[HTML][HTML] Glycemic variability: clinical implications

SVS Krishna, SK Kota, KD Modi - Indian journal of endocrinology …, 2013 - journals.lww.com
Glycemic control and its benefits in preventing microvascular diabetic complications are
convincingly proved by various prospective trials. Diabetes control and complications trial …

Regulation of SERCA pumps expression in diabetes

A Zarain-Herzberg, G García-Rivas, R Estrada-Avilés - Cell Calcium, 2014 - Elsevier
Abstract Cytosolic calcium concentration ([Ca 2+] c) is fundamental for regulation of many
cellular processes such metabolism, proliferation, muscle contraction, cell signaling and …

[HTML][HTML] Implications of serum paraoxonase activity in obesity, diabetes mellitus, and dyslipidemia

SK Kota, LK Meher, SK Kota, S Jammula… - Indian journal of …, 2013 - journals.lww.com
Abstract Human serum paraoxonase 1 (PON1) is an enzyme with esterase activity, and is
physically bound to high-density lipoproteins (HDL). It plays a key role in the action of HDL …

[HTML][HTML] Carotid intima media thickness in type 2 diabetes mellitus with ischemic stroke

SK Kota, GB Mahapatra, SK Kota… - Indian journal of …, 2013 - journals.lww.com
Background: Diabetes mellitus is associated with high cardiovascular risk. Carotid intima
media thickness (CIMT) is used commonly as a noninvasive test for the assessment of …

[HTML][HTML] Ca2+ mishandling and mitochondrial dysfunction: a converging road to prediabetic and diabetic cardiomyopathy

C Jaquenod De Giusti, J Palomeque… - Pflügers Archiv-European …, 2022 - Springer
Diabetic cardiomyopathy is defined as the myocardial dysfunction that suffers patients with
diabetes mellitus (DM) in the absence of hypertension and structural heart diseases such as …

[HTML][HTML] Saxagliptin restores vascular mitochondrial exercise response in the Goto-Kakizaki rat

AC Keller, LA Knaub, MW Miller, N Birdsey… - Journal of …, 2015 - journals.lww.com
Cardiovascular disease risk and all-cause mortality are largely predicted by physical fitness.
Exercise stimulates vascular mitochondrial biogenesis through endothelial nitric oxide …