MicroRNA signatures in human ovarian cancer

MV Iorio, R Visone, G Di Leva, V Donati, F Petrocca… - Cancer research, 2007 - AACR
Epithelial ovarian cancer (EOC) is the sixth most common cancer in women worldwide and,
despite advances in detection and therapies, it still represents the most lethal gynecologic …

2'deoxy-2'-alkylnucleotide containing nucleic acid

N Usman, A Karpeisky, L Beigelman… - US Patent 5,627,053, 1997 - Google Patents
This application is a continuation-in-part of Usman et al., having the same title as above,
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Human thrombospondin polypeptide

L Mintz, H Xie, D Dahary, E Levanon, S Freilich… - US Patent …, 2010 - Google Patents
the present invention relates to systems and methods useful for annotating biomolecular
sequences. More particularly, the present invention relates to computational approaches …

Enzymatic nucleic acids containing 5'-and/or 3'-cap structures

J Matulic-Adamic, L Beigelman, A Karpeisky… - US Patent …, 1999 - Google Patents
US5998203A - Enzymatic nucleic acids containing 5'-and/or 3'-cap structures - Google Patents
US5998203A - Enzymatic nucleic acids containing 5'-and/or 3'-cap structures - Google Patents …

Lipids, lipid compositions, and methods of using them

J Baryza, K Bowman, A Geall, T Labonte… - US Patent App. 12 …, 2011 - Google Patents
2010-12-21 Assigned to NOVARTIS AG reassignment NOVARTIS AG ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ZHAO, JUNPING …

Conjugates and compositions for cellular delivery

C Vargeese, P Haeberli, W Wang, T Chen - US Patent 7,491,805, 2009 - Google Patents
0* CC (CC ([12*]) C) N ([8*]) C (= O) CCN ([3*]) C (= O) CCC (C) N ([5*]) C (= O) C1= CC= C
(N ([6*]) CC2= NC3= C (N= C2) N= C (C) NC3= O) C= C1 Chemical compound* CC (CC …

Amino lipids and methods for the delivery of nucleic acids

MJ Hope, SC Semple, J Chen, TD Madden… - US Patent …, 2015 - Google Patents
Related US Application Data Gong and Lin," A glassy carbon Supported bilayer lipid-like
mem brane of 5.5-diteradecyl-2-(2-trimethyl-ammonioethyl)-1, 3-(60) Provisional application …

Conjugates and compositions for cellular delivery

C Vargeese, P Haeberli, W Wang, T Chen - US Patent 7,833,992, 2010 - Google Patents
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US7833992B2 - Conjugates and compositions for cellular delivery - Google Patents Conjugates …

2'-O-alkylthioalkyl and 2-C-alkylthioalkyl-containing enzymatic nucleic acids (ribozymes)

L Beigelman, A Karpeisky - US Patent 5,716,824, 1998 - Google Patents
R2-0 wherein, R1 represents 2'-OR-thio-R and/or 2-CR-thio R, wherein R is independently a
moiety selected from a group consisting of alkyl, alkenyl, alkynyl, aryl, alkylaryl. carbocyclic …

Amino lipids and methods for the delivery of nucleic acids

MJ Hope, SC Semple, J Chen, TD Madden… - US Patent …, 2020 - Google Patents
US10653780B2 - Amino lipids and methods for the delivery of nucleic acids - Google
Patents US10653780B2 - Amino lipids and methods for the delivery of nucleic acids …