Extraintestinal manifestations of inflammatory bowel disease: current concepts, treatment, and implications for disease management

G Rogler, A Singh, A Kavanaugh, DT Rubin - Gastroenterology, 2021 - Elsevier
Inflammatory bowel diseases (IBDs) are systemic diseases that manifest not only in the gut
and gastrointestinal tract, but also in the extraintestinal organs in many patients. The quality …

Genetics of inflammatory bowel diseases

DPB McGovern, S Kugathasan, JH Cho - Gastroenterology, 2015 - Elsevier
In this review, we provide an update on genome-wide association studies (GWAS) in
inflammatory bowel disease (IBD). In addition, we summarize progress in defining the …

Pyoderma gangrenosum: an update on pathophysiology, diagnosis and treatment

A Alavi, LE French, MD Davis, A Brassard… - American journal of …, 2017 - Springer
Pyoderma gangrenosum (PG) is a rare inflammatory neutrophilic disorder with prototypical
clinical presentations. Its pathophysiology is complex and not fully explained. Recent …

Pathophysiology of pyoderma gangrenosum (PG): an updated review

SF Braswell, TC Kostopoulos… - Journal of the American …, 2015 - Elsevier
Pyoderma gangrenosum is a challenging skin condition to identify and treat because of its
multifactorial pathogenesis. It is a rare cutaneous manifestation diagnosed clinically by …

The pathogenesis of extraintestinal manifestations: implications for IBD research, diagnosis, and therapy

CRH Hedin, SR Vavricka, AJ Stagg… - Journal of Crohn's …, 2019 - academic.oup.com
This article reports on the sixth scientific workshop of the European Crohn's and Colitis
Organisation [ECCO] on the pathogenesis of extraintestinal manifestations [EIMs] in …

ECCO guidelines on extraintestinal manifestations in inflammatory bowel disease

H Gordon, J Burisch, P Ellul, K Karmiris… - Journal of Crohn's …, 2024 - academic.oup.com
This is the second European Crohn's and Colitis Organisation [ECCO] evidence-based
consensus on extraintestinal manifestations [EIMs] of inflammatory bowel disease [IBD] and …

Pyoderma gangrenosum: a review of pathogenesis and treatment

C Ahn, D Negus, W Huang - Expert review of clinical immunology, 2018 - Taylor & Francis
Introduction: Pyoderma gangrenosum (PG) is a complex neutrophilic dermatosis that can
occur as an idiopathic disease, in association with systemic conditions such as inflammatory …

Genetics of inflammatory bowel disease: beyond NOD2

MU Mirkov, B Verstockt, I Cleynen - The lancet Gastroenterology & …, 2017 - thelancet.com
The study of the genetic underpinnings of inflammatory bowel disease has made great
progress since the identification of NOD2 as a major susceptibility gene. Novel genotyping …

Skin manifestations of inflammatory bowel disease

T Greuter, A Navarini, SR Vavricka - Clinical reviews in allergy & …, 2017 - Springer
Inflammatory bowel disease (IBD) with its two main subtypes Crohn's disease and ulcerative
colitis is not restricted to the gastrointestinal tract. Indeed, so-called extraintestinal …

Diagnosis and management of peristomal pyoderma gangrenosum: a systematic review

L Afifi, IM Sanchez, MM Wallace, SF Braswell… - Journal of the American …, 2018 - Elsevier
Background Peristomal pyoderma gangrenosum (PPG) is an uncommon subtype of
pyoderma gangrenosum. PPG is a challenging condition to diagnose and treat; no evidence …