The hallmark of eukaryotic cells is the nucleus that contains the genome, enclosed by a
physical barrier known as the nuclear envelope (NE). On the one hand, this …

Controlled nano-systems for drug delivery are designed to deliver therapeutical drugs to
desirable sites on demand. Due to the diverse physiological functions of peptides, it is …

Nuclear pore complexes (NPCs) embedded within the nuclear envelope mediate rapid,
selective and bidirectional traffic between the cytoplasm and the nucleoplasm. Deciphering …

The transient nature of RNA has rendered it one of the more difficult biological targets for
imaging. This difficulty stems both from the physical properties of RNA as well as the …

Transport of membrane and cytosolic proteins into the primary cilium is essential for its role
in cellular signaling. Using virtual three-dimensional superresolution light microscopy, the …

The nuclear pore complex (NPC) employs the intrinsically disordered regions (IDRs) from a
family of phenylalanine-glycine-rich nucleoporins (FG-Nups) to control nucleocytoplasmic …

ABSTRACT The Nuclear Pore Complex (NPC) represents a critical passage through the
nuclear envelope for nuclear import and export that impacts nearly every cellular process at …

Sitting on the nuclear envelope, nuclear pore complexes (NPCs) control the molecular
transport between the nucleus and the cytoplasm. Without definite open or close states, the …

Both natively folded and intrinsically disordered proteins (IDPs) destined for the nucleus
need to transport through the nuclear pore complexes (NPCs) in eukaryotic cells. NPCs …

The cilium, a pivotal organelle crucial for cell signaling and proper cell function, relies on
meticulous macromolecular transport from the cytoplasm for its formation and maintenance …