Bottom-up proteomics: advancements in sample preparation
Liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based proteomics is a
powerful technique for profiling proteomes of cells, tissues, and body fluids. Typical bottom …
powerful technique for profiling proteomes of cells, tissues, and body fluids. Typical bottom …
Making proteomics data accessible and reusable: current state of proteomics databases and repositories
Y Perez‐Riverol, E Alpi, R Wang, H Hermjakob… - …, 2015 - Wiley Online Library
Compared to other data‐intensive disciplines such as genomics, public deposition and
storage of MS‐based proteomics, data are still less developed due to, among other reasons …
storage of MS‐based proteomics, data are still less developed due to, among other reasons …
Review of three-dimensional liquid chromatography platforms for bottom-up proteomics
Proteomics is a large-scale study of proteins, aiming at the description and characterization
of all expressed proteins in biological systems. The expressed proteins are typically highly …
of all expressed proteins in biological systems. The expressed proteins are typically highly …
Marine organisms as potential sources of bioactive peptides that inhibit the activity of angiotensin I-converting enzyme: a review
Angiotensin I-converting enzyme (ACE) is a paramount therapeutic target to treat
hypertension. ACE inhibitory peptides derived from food protein sources are regarded as …
hypertension. ACE inhibitory peptides derived from food protein sources are regarded as …
In-depth analysis of protein inference algorithms using multiple search engines and well-defined metrics
In mass spectrometry-based shotgun proteomics, protein identifications are usually the
desired result. However, most of the analytical methods are based on the identification of …
desired result. However, most of the analytical methods are based on the identification of …
Qualitative and quantitative characterization of protein biotherapeutics with liquid chromatography mass spectrometry
In the last decade, the advancement of liquid chromatography mass spectrometry (LC/MS)
techniques has enabled their broad application in protein characterization, both …
techniques has enabled their broad application in protein characterization, both …
Accurate quantitative proteomic analyses using metabolic labeling and high field asymmetric waveform ion mobility spectrometry (FAIMS)
S Pfammatter, E Bonneil, FP McManus… - Journal of proteome …, 2019 - ACS Publications
Stable isotope labeling by amino acids in cell culture (SILAC) is routinely used to profile
changes in protein and peptide abundance across different experimental paradigms. As with …
changes in protein and peptide abundance across different experimental paradigms. As with …
3D HPLC-MS with reversed-phase separation functionality in all three dimensions for large-scale bottom-up proteomics and peptide retention data collection
V Spicer, P Ezzati, H Neustaeter, RC Beavis… - Analytical …, 2016 - ACS Publications
The growing complexity of proteomics samples and the desire for deeper analysis drive the
development of both better MS instrument and advanced multidimensional separation …
development of both better MS instrument and advanced multidimensional separation …
First Report of Screening of Novel Angiotensin-I Converting Enzyme Inhibitory Peptides Derived from the Red Alga Acrochaetium sp.
ACE inhibitors generated from food proteins have recently become the most well-known
subclass of bioactive peptides, and their bio-functionality can be a potential alternative to …
subclass of bioactive peptides, and their bio-functionality can be a potential alternative to …
[HTML][HTML] Spermine and spermidine reversed age-related cardiac deterioration in rats
H Zhang, J Wang, L Li, N Chai, Y Chen, F Wu… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Aging is the most important risk factor for cardiovascular disease (CVD). Slowing or
reversing the physiological impact of heart aging may reduce morbidity and mortality …
reversing the physiological impact of heart aging may reduce morbidity and mortality …