Viral vectored vaccines: design, development, preventive and therapeutic applications in human diseases

S Wang, B Liang, W Wang, L Li, N Feng… - Signal transduction and …, 2023 - nature.com
Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …

Newcastle disease vaccines—A solved problem or a continuous challenge?

KM Dimitrov, CL Afonso, Q Yu, PJ Miller - Veterinary microbiology, 2017 - Elsevier
Newcastle disease (ND) has been defined by the World Organisation for Animal Health as
infection of poultry with virulent strains of Newcastle disease virus (NDV). Lesions affecting …

Newcastle disease virus: current status and our understanding

K Ganar, M Das, S Sinha, S Kumar - Virus research, 2014 - Elsevier
Newcastle disease (ND) is one of the highly pathogenic viral diseases of avian species. ND
is economically significant because of the huge mortality and morbidity associated with it …

A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses

W Sun, Y Liu, F Amanat, I González-Domínguez… - Nature …, 2021 - nature.com
Rapid development of COVID-19 vaccines has helped mitigating SARS-CoV-2 spread, but
more equitable allocation of vaccines is necessary to limit the global impact of the COVID-19 …

Newcastle disease virus as a vaccine vector for development of human and veterinary vaccines

SH Kim, SK Samal - Viruses, 2016 - mdpi.com
Viral vaccine vectors have shown to be effective in inducing a robust immune response
against the vaccine antigen. Newcastle disease virus (NDV), an avian paramyxovirus, is a …

Immunogenicity and protective efficacy of an intranasal live-attenuated vaccine against SARS-CoV-2

JG Park, FS Oladunni, MA Rohaim… - IScience, 2021 - cell.com
Global deployment of an effective and safe vaccine is necessary to curtail the coronavirus
disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 …

A recombinant Newcastle disease virus (NDV) expressing S protein of infectious bronchitis virus (IBV) protects chickens against IBV and NDV

E Shirvani, A Paldurai, VK Manoharan, BP Varghese… - Scientific reports, 2018 - nature.com
Infectious bronchitis virus (IBV) causes a highly contagious respiratory, reproductive and
urogenital tract disease in chickens worldwide, resulting in substantial economic losses for …

[HTML][HTML] Reverse genetics of Mononegavirales: How they work, new vaccines, and new cancer therapeutics

CK Pfaller, R Cattaneo, MJ Schnell - Virology, 2015 - Elsevier
The order Mononegavirales includes five families: Bornaviridae, Filoviridae, Nyamaviridae,
Paramyxoviridae, and Rhabdoviridae. The genome of these viruses is one molecule of …

Unique type I interferon responses determine the functional fate of migratory lung dendritic cells during influenza virus infection

B Moltedo, W Li, JS Yount, TM Moran - PLoS pathogens, 2011 - journals.plos.org
Migratory lung dendritic cells (DCs) transport viral antigen from the lungs to the draining
mediastinal lymph nodes (MLNs) during influenza virus infection to initiate the adaptive …

Newcastle disease virus as a vaccine vector for 20 years: a focus on maternally derived antibody interference

Z Hu, J Ni, Y Cao, X Liu - Vaccines, 2020 - mdpi.com
It has been 20 years since Newcastle disease virus (NDV) was first used as a vector. The
past two decades have witnessed remarkable progress in vaccine generation based on the …