Bleeding complications arising from trauma, surgery, and as congenital, disease‐
associated, or drug‐induced blood disorders can cause significant morbidities and …

Severe hemorrhage has posed a serious threat to the health and even life of civilian and
military populations and brought serious economic losses. Consequently, it is imperative to …

Whole blood is the preferred product for resuscitation of severe traumatic hemorrhage. It
contains all the elements of blood that are necessary for oxygen delivery and hemostasis, in …

BACKGROUND: Use of whole blood (WB) for trauma resuscitation has seen a resurgence.
The purpose of this study was to investigate survival benefit of WB across a diverse …

Donor organ allocation is dependent on ABO matching, restricting the opportunity for some
patients to receive a life-saving transplant. The enzymes FpGalNAc deacetylase and …

Introduction: Platelet refrigeration decreases the risk of bacterial contamination and may
preserve function better than standard-of-care room temperature (RT) storage. Benefits …

Background This pilot trial focused on feasibility and safety to provide preliminary data to
evaluate the hemostatic potential of cold-stored platelets (2° to 6° C) compared with …

Background New concepts in resuscitation from hemorrhagic shock (or renewed interest in
older concepts) have been emerging in recent years. A report from 1993 noted that initial …

Importance Whole-blood (WB) resuscitation has gained renewed interest among civilian
trauma centers. However, there remains insufficient evidence that WB as an adjunct to …

Recent combat experience reignited interest in transfusing whole blood (WB) for patients
with life‐threatening bleeding. US Army data indicate that WB transfusion is associated with …