Fungal diseases largely affect human and animal health and dramatically diminish food crop
yields [1]. Among fungi, systemic Candida infections are the second or third most common …

Aneuploidy is a cellular state with an unbalanced chromosome number that deviates from
the usual euploid status. During evolution, elaborate cellular mechanisms have evolved to …

Expanding echinocandin use to prevent or treat invasive fungal infections has led to an
increase in the number of breakthrough infections due to resistant Candida species …

How cells exposed to one stress are later able to better survive other types of stress is not
well understood. In eukaryotic organisms, physiological and pathological stresses can …

Candida albicans is a prevailing fungal pathogen with a diploid genome that can adapt to
environmental stresses by losing or gaining an entire chromosome or a large portion of a …

Dosage compensation, the equalized X chromosome gene expression between males and
females in Drosophila, has also been found in triple X metafemales. Inverse dosage effects …

Candida albicans is a prevalent fungal pathogen of humans. Understanding the
development of decreased susceptibility to ECN drugs of this microbe is of substantial …

Candida albicans is an important fungal pathogen with a diploid genome that can adapt to
caspofungin, a major drug from the echinocandin class, by a reversible loss of one copy of …

Candida albicans is a diploid fungus and a predominant opportunistic human pathogen.
Notably, C. albicans employs reversible chromosomal aneuploidies as a means of survival …

Candida albicans, a fungus that normally inhabits the digestive tract and other mucosal
surfaces, can become a pathogen in immunocompromised individuals, causing severe or …