The challenge of establishing preclinical models for segmental bone defect research

JC Reichert, S Saifzadeh, ME Wullschleger, DR Epari… - Biomaterials, 2009 - Elsevier
A considerable number of international research groups as well as commercial entities work
on the development of new bone grafting materials, carriers, growth factors and specifically …

Reamer-irrigator-aspirator indications and clinical results: a systematic review

G Cox, E Jones, D McGonagle… - International orthopaedics, 2011 - Springer
Background The 'reamer-irrigator-aspirator'(RIA) is an innovation developed to reduce fat
embolism (FE) and thermal necrosis (TN) that can occur during reaming/nailing of long-bone …

Quantitative assessment of growth factors in reaming aspirate, iliac crest, and platelet preparation

G Schmidmaier, S Herrmann, J Green, T Weber… - Bone, 2006 - Elsevier
Large bony defects and non-unions are still a complication in trauma and orthopedic
surgery. Treatment strategies include the use of autogenous materials (iliac crest), allogenic …

Qualitative and quantitative differences between bone graft obtained from the medullary canal (with a Reamer/Irrigator/Aspirator) and the iliac crest of the same patient

HC Sagi, ML Young, L Gerstenfeld, TA Einhorn… - JBJS, 2012 - journals.lww.com
Background: Donor site morbidity and limited volume remain primary drawbacks of using
bone graft from the iliac crest and an impetus for finding other sources of autologous bone …

Human reaming debris: a source of multipotent stem cells

S Wenisch, K Trinkaus, A Hild, D Hose, K Herde… - Bone, 2005 - Elsevier
The biological characteristics of human reaming debris (HRD) generated in the course of
surgical treatment of long bone diaphyseal fractures and nonunions are still a matter of …

Principles of nonunion management: state of the art

A Nauth, M Lee, MJ Gardner, MR Brinker… - Journal of …, 2018 - journals.lww.com
A substantial proportion of fractures can present with nonunion, and the management of
nonunion continues to present a challenge for orthopaedic surgeons. A variety of biological …

The biological and physiological effects of intramedullary reaming

HC Pape, P Giannoudis - The Journal of Bone & Joint Surgery …, 2007 - boneandjoint.org.uk
This paper summarises the current knowledge on the effects of medullary reaming of long-
bone fractures. Following a review of intramedullary vascular physiology, the consequences …

Viable osteoblastic potential of cortical reamings from intramedullary nailing

JPM Frölke, JK Nulend, CM Semeins… - Journal of …, 2004 - Wiley Online Library
To analyze the effect of intramedullary reaming on fracture healing, we investigated whether
or not cortical reamings contain viable bone cells. There are several tissue components …

Donor site morbidity with reamer-irrigator-aspirator (RIA) use for autogenous bone graft harvesting in a single centre 204 case series

LM Qvick, CA Ritter, CE Mutty, BJ Rohrbacher… - Injury, 2013 - Elsevier
Donor site morbidity and complication rate using the reamer-irrigator-aspirator (RIA) system
for intramedullary, non-structural autogenous bone graft harvesting were investigated in a …

Complications associated with negative pressure reaming for harvesting autologous bone graft: a case series

JA Lowe, GJ Della Rocca, Y Murtha… - … of orthopaedic trauma, 2010 - journals.lww.com
A technical benefit of the reamer-irrigator-aspirator (RIA) system (Synthes, Paoli, PA) is the
ability to harvest large volumes (40-90 cm 3) of autogenous bone graft. Early evaluations of …