Resting-state functional MR imaging: a new window to the brain

F Barkhof, S Haller, SARB Rombouts - Radiology, 2014 - pubs.rsna.org
Resting-state (RS) functional magnetic resonance (MR) imaging constitutes a novel
paradigm that examines spontaneous brain function by using blood oxygen level …

Cognitive impairment in multiple sclerosis–a review of current knowledge and recent research

T Grzegorski, J Losy - Reviews in the Neurosciences, 2017 - degruyter.com
Multiple sclerosis (MS) is a chronic, progressive disease of the central nervous system that is
characterised by inflammatory damage to the myelin sheath. Though often neglected …

Age and disability drive cognitive impairment in multiple sclerosis across disease subtypes

L Ruano, E Portaccio, B Goretti… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Background: There is limited and inconsistent information on the clinical determinants of
cognitive impairment (CI) in multiple sclerosis (MS). Objective: The aim of this study was to …

Network collapse and cognitive impairment in multiple sclerosis

MM Schoonheim, KA Meijer, JJG Geurts - Frontiers in neurology, 2015 - frontiersin.org
The current field of multiple sclerosis (MS) research is an active and highly interesting one:
structural abnormalities such as inflammatory lesions and brain atrophy are studied with a …

Thalamus structure and function determine severity of cognitive impairment in multiple sclerosis

MM Schoonheim, HE Hulst, RB Brandt, M Strik… - Neurology, 2015 - AAN Enterprises
Objective: This study investigates whether changes in functional connectivity, diffusivity, and
volume of the thalamus can explain different severities of cognitive impairment in multiple …

Diffusion tensor tractography reveals disrupted topological efficiency in white matter structural networks in multiple sclerosis

N Shu, Y Liu, K Li, Y Duan, J Wang, C Yu… - Cerebral …, 2011 - academic.oup.com
Little is currently known about the alterations in the topological organization of the white
matter (WM) structural networks in patients with multiple sclerosis (MS). In the present study …

Virtual reality-based therapy improves fatigue, impact, and quality of life in patients with multiple sclerosis. A systematic review with a meta-analysis

I Cortés-Pérez, M Sánchez-Alcalá, FA Nieto-Escámez… - Sensors, 2021 - mdpi.com
Patients with multiple sclerosis (PwMS) have a high level of fatigue and a reduced quality of
life (QoL) due to the impact of multiple sclerosis (MS). Virtual reality-based therapy (VRBT) is …

Distinct cognitive impairments in different disease courses of multiple sclerosis—A systematic review and meta-analysis

A Johnen, NC Landmeyer, PC Bürkner… - Neuroscience & …, 2017 - Elsevier
Cognitive impairment (CI) is common and debilitating in patients with multiple sclerosis.
However, little is known about how different disease courses affect CI, impeding prognosis …

Interplay between age and neuroinflammation in multiple sclerosis: effects on motor and cognitive functions

A Musella, A Gentile, FR Rizzo, F De Vito… - Frontiers in aging …, 2018 - frontiersin.org
Aging is one of the main risk factors for the development of many neurodegenerative
diseases. Emerging evidence has acknowledged neuroinflammation as potential trigger of …

[HTML][HTML] Task-and resting-state fMRI studies in multiple sclerosis: From regions to systems and time-varying analysis. Current status and future perspective

MA Rocca, MM Schoonheim, P Valsasina… - Neuroimage: Clinical, 2022 - Elsevier
Multiple sclerosis (MS) is a neurological disorder affecting the central nervous system and
features extensive functional brain changes that are poorly understood but relate strongly to …