Circulating tumor cell-blood cell crosstalk: Biology and clinical relevance

T Pereira-Veiga, S Schneegans, K Pantel, H Wikman - Cell Reports, 2022 - cell.com
Circulating tumor cells (CTCs) are the seeds of distant metastasis, and the number of CTCs
detected in the blood of cancer patients is associated with a worse prognosis. CTCs face …

Tumor microenvironment participates in metastasis of pancreatic cancer

B Ren, M Cui, G Yang, H Wang, M Feng, L You… - Molecular cancer, 2018 - Springer
Pancreatic cancer is a deadly disease with high mortality due to difficulties in its early
diagnosis and metastasis. The tumor microenvironment induced by interactions between …

[HTML][HTML] Tumor microenvironment in chemoresistance, metastasis and immunotherapy of pancreatic cancer

S Wang, Y Li, C Xing, C Ding, H Zhang… - American journal of …, 2020 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is a fatal disease with high malignancy and difficult for early
diagnosis. PC causes more than 400,000 patient deaths world widely and becomes the …

Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target

JW Franses, J Philipp, P Missios, I Bhan, A Liu… - Nature …, 2020 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) lethality is due to metastatic dissemination.
Characterization of rare, heterogeneous circulating tumor cells (CTCs) can provide insight …

Liquid biopsy in pancreatic cancer–Current perspective and future outlook

Y Zhao, J Tang, K Jiang, SY Liu, A Aicher… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Pancreatic cancer is a lethal condition with a rising incidence and often presents at an
advanced stage, contributing to abysmal five-year survival rates. Unspecific symptoms and …

Current status of the diagnosis of early-stage pancreatic ductal adenocarcinoma

K Nakaoka, E Ohno, N Kawabe, T Kuzuya, K Funasaka… - Diagnostics, 2023 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) can be treated with surgery, chemotherapy, and
radiotherapy. Despite medical progress in each field in recent years, it is still insufficient for …

Circulating tumor cells in the early detection of human cancers

Z Feng, Y Feng, N Wang - Handbook of Cancer and Immunology, 2022 - Springer
Cancer is considered as the leading cause of death and the major barrier of longevity
globally. The high mortality of cancer is due to the malignant spread. However, if the disease …

Exploring the clinical utility of pancreatic cancer circulating tumor cells

D Yeo, A Bastian, H Strauss, P Saxena… - International Journal of …, 2022 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is the most frequent pancreatic cancer type,
characterized by a dismal prognosis due to late diagnosis, frequent metastases, and limited …

[HTML][HTML] Early diagnosis of pancreatic cancer: What strategies to avoid a foretold catastrophe

V Tonini, M Zanni - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
While great strides in improving survival rates have been made for most cancers in recent
years, pancreatic ductal adenocarcinoma (PDAC) remains one of the solid tumors with the …

GNAS mutation detection in circulating cell-free DNA is a specific predictor for intraductal papillary mucinous neoplasms of the pancreas, especially for intestinal …

T Hata, M Mizuma, F Motoi, Y Omori, M Ishida… - Scientific reports, 2020 - nature.com
Pancreatic cystic neoplasms (PCNs) are a heterogeneous group with varying risks of
malignancy. To explore the clinical utility of liquid biopsy in cyst type classification, we …