The human oral cavity is home to an abundant and diverse microbial community (ie, the oral
microbiome), whose composition and roles in health and disease have been the focus of …

With this review, we aim to increase the quality standards for clinical studies with
microbiome as an output parameter. We critically address the existing body of evidence for …

Background The microbiome of the oral cavity is the second-largest and diverse microbiota
after the gut, harboring over 700 species of bacteria and including also fungi, viruses, and …

Amplification and sequencing of 16S amplicons are widely used for profiling the structure of
oral microbiota. However, it remains not clear whether and to what degree DNA extraction …

Background The oral cavity comprises a rich and diverse microbiome, which plays important
roles in health and disease. Previous studies have mostly focused on adult populations or in …

The oral microbiome can play a role in the instigation and progression of oral diseases that
can manifest into other systemic conditions. These associations encourage the exploration …

An altered oral microbiota has been linked with the development of several oral diseases,
such as dental caries, periodontal disease, and oral stomatitis. Moreover, poor oral health …

The relevance of the human oral microbiome to our understanding of human health has
grown in recent years as microbiome studies continue to develop. Given the links of the oral …

The exploration of oral microbiome has been increasing due to its relatedness with various
systemic diseases, but standardization of saliva sampling for microbiome analysis has not …

Saliva testing is a vital method for clinical applications, for its noninvasive features, richness
in substances, and the huge amount. Due to its direct anatomical connection with oral …