Deep brain stimulation in addiction: a review of potential brain targets

J Luigjes, W Van Den Brink, M Feenstra… - Molecular …, 2012 - nature.com
Deep brain stimulation (DBS) is an adjustable, reversible, non-destructive neurosurgical
intervention using implanted electrodes to deliver electrical pulses to areas in the brain. DBS …

Compulsivity in anorexia nervosa: a transdiagnostic concept

LR Godier, RJ Park - Frontiers in psychology, 2014 - frontiersin.org
The compulsive nature of weight loss behaviors central to anorexia nervosa (AN), such as
relentless self-starvation and over-exercise, has led to the suggestion of parallels between …

[HTML][HTML] Preclinical and clinical evidence for suppression of alcohol intake by apremilast

KB Grigsby, RA Mangieri, AJ Roberts… - The Journal of …, 2023 - Am Soc Clin Investig
JCI - Preclinical and clinical evidence for suppression of alcohol intake by apremilast Go to
JCI Insight About Editors Consulting Editors For authors Publication ethics Alerts Advertising …

Deep brain stimulation of the nucleus accumbens in treatment-resistant alcohol use disorder: a double-blind randomized controlled multi-center trial

P Bach, M Luderer, UJ Müller, M Jakobs… - Translational …, 2023 - nature.com
Abstract Treatment resistance in alcohol use disorders (AUD) is a major problem for affected
individuals and for society. In the search of new treatment options, few case studies using …

Deep brain stimulation for the treatment of drug addiction

TR Wang, S Moosa, RF Dallapiazza, WJ Elias… - Neurosurgical …, 2018 - thejns.org
Drug addiction represents a significant public health concern that has high rates of relapse
despite optimal medical therapy and rehabilitation support. New therapies are needed, and …

Brain stimulation in addiction

MC Salling, D Martinez - Neuropsychopharmacology, 2016 - nature.com
Localized stimulation of the human brain to treat neuropsychiatric disorders has been in
place for over 20 years. Although these methods have been used to a greater extent for …

Amelioration of binge eating by nucleus accumbens shell deep brain stimulation in mice involves D2 receptor modulation

CH Halpern, A Tekriwal, J Santollo… - Journal of …, 2013 - Soc Neuroscience
Hedonic overconsumption contributing to obesity involves altered activation within the
mesolimbic dopamine system. Dysregulation of dopamine signaling in the nucleus …

Successful deep brain stimulation of the nucleus accumbens in severe alcohol dependence is associated with changed performance monitoring

J Kuhn, TOJ Gründler, R Bauer, W Huff… - Addiction …, 2011 - Wiley Online Library
Following recent advances in neuromodulation therapy for mental disorders, we treated one
patient with severe alcohol addiction with deep brain stimulation (DBS) of the nucleus …

Deep brain stimulation for psychiatric disease: contributions and validity of animal models

C Hamani, Y Temel - Science translational medicine, 2012 - science.org
During treatment with deep brain stimulation (DBS), electrical current is delivered into the
brain parenchyma through implanted electrodes. Although this technique is routinely used in …

[HTML][HTML] Deep brain stimulation for addictive disorders—where are we now?

J Yuen, AZ Kouzani, M Berk, SJ Tye, AE Rusheen… - …, 2022 - Elsevier
In the face of a global epidemic of drug addiction, neglecting to develop new effective
therapies will perpetuate the staggering human and economic costs of substance use. This …