Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a
major cause of morbidity and mortality. The circadian timing system consists of a central …

The circadian system generates endogenous rhythms of approximately 24 h, the
synchronisation of which are vital for healthy bodily function. The timing of many …

Melatonin is a ubiquitous molecule present in almost every live being from bacteria to
humans. In vertebrates, besides being produced in peripheral tissues and acting as an …

A large body of epidemiologic evidence has linked insufficient sleep duration and quality to
the risk of obesity, insulin resistance and type 2 diabetes. To address putative causal …

(1) Background: Eating is fundamental to survival. Animals choose when to eat depending
on food availability. The timing of eating can synchronize different organs and tissues that …

Despite considerable advances in the past few years, obesity and type 2 diabetes mellitus
(T2DM) remain two major challenges for public health systems globally. In the past 9 years …

A systematic literature review and meta-analyses (where appropriate) were performed and
the GRADE approach was used to update the previous American Academy of Sleep …

Weight gain, obesity and diabetes have reached alarming levels in the developed world.
Traditional risk factors such as over‐eating, poor nutritional choices and lack of exercise …

Glucose tolerance is lower in the evening and at night than in the morning. However, the
relative contribution of the circadian system vs. the behavioral cycle (including the …

The circadian system serves one of the most fundamental properties present in nearly all
organisms: it generates 24-h rhythms in behavioral and physiological processes and …