Heart failure with preserved ejection fraction (HFpEF) affects half of all patients with heart
failure worldwide, is increasing in prevalence, confers substantial morbidity and mortality …

Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

This review aims to provide a translational perspective on recent developments in heart
failure with preserved ejection fraction (HFpEF), linking mechanistic insights to potential …

The multifunctional membrane glycoprotein CD36 is expressed in different types of cells and
plays a key regulatory role in cellular lipid metabolism, especially in cardiac muscle. CD36 …

An important aspect of precision medicine is to probe the stability in molecular profiles
among healthy individuals over time. Here, we sample a longitudinal wellness cohort with …

Background Comorbidities are common in patients with heart failure (HF) and complicate
treatment and outcomes. We identified patterns of multimorbidity in Asian patients with HF …

Heart failure (HF) patients often suffer from multiple comorbidities, such as diabetes, atrial
fibrillation, depression, chronic obstructive pulmonary disease, and chronic kidney disease …

Fatty acids and glucose are the main substrates for myocardial energy provision. Under
physiologic conditions, there is a distinct and finely tuned balance between the utilization of …

Heart failure (HF) leads to an increase in morbidity and mortality globally. Disorders of
energy metabolism and apoptosis of cardiomyocytes are critically involved in the …

Chagas disease (CD) is a parasitic disease caused by Trypanosoma cruzi protozoa,
presenting with cardiomyopathy, megaesophagus, and/or megacolon. To determine the …