Chemistry for Positron Emission Tomography: Recent Advances in 11C‐, 18F‐, 13N‐, and 15O‐Labeling Reactions
X Deng, J Rong, L Wang, N Vasdev… - Angewandte Chemie …, 2019 - Wiley Online Library
Positron emission tomography (PET) is a molecular imaging technology that provides
quantitative information about function and metabolism in biological processes in vivo for …
quantitative information about function and metabolism in biological processes in vivo for …
Copper-mediated late-stage radiofluorination: five years of impact on preclinical and clinical PET imaging
Purpose Copper-mediated radiofluorination (CMRF) is emerging as the method of choice for
the formation of aromatic C–18 F bonds. This minireview examines proof-of-concept …
the formation of aromatic C–18 F bonds. This minireview examines proof-of-concept …
New methodologies for the preparation of carbon-11 labeled radiopharmaceuticals
K Dahl, C Halldin, M Schou - Clinical and Translational Imaging, 2017 - Springer
Purpose This short review aims to cover the more recent and promising developments of
carbon-11 (11 C) labeling radiochemistry and its utility in the production of novel …
carbon-11 (11 C) labeling radiochemistry and its utility in the production of novel …
11 C [double bond, length as m-dash] O bonds made easily for positron emission tomography radiopharmaceuticals
The positron-emitting radionuclide carbon-11 (11C, t1/2= 20.3 min) possesses the unique
potential for radiolabeling of any biological, naturally occurring, or synthetic organic …
potential for radiolabeling of any biological, naturally occurring, or synthetic organic …
Recent progress in [11C]carbon dioxide ([11C]CO2) and [11C]carbon monoxide ([11C]CO) chemistry
C Taddei, AD Gee - Journal of Labelled Compounds and …, 2018 - Wiley Online Library
[11C] Carbon dioxide ([11C] CO2) and [11C] carbon monoxide ([11C] CO) are 2 attractive
precursors for labelling the carbonyl position (C═ O) in a vast range of functionalised …
precursors for labelling the carbonyl position (C═ O) in a vast range of functionalised …
Carboxylation of Aryl Triflates with CO2 Merging Palladium and Visible-Light-Photoredox Catalysts
We report herein a visible-light-promoted, highly practical carboxylation of readily accessible
aryl triflates at ambient temperature and a balloon pressure of CO2 by the combined use of …
aryl triflates at ambient temperature and a balloon pressure of CO2 by the combined use of …
Recent developments in carbon-11 chemistry and applications for first-in-human PET studies
A Pees, M Chassé, A Lindberg, N Vasdev - Molecules, 2023 - mdpi.com
Positron emission tomography (PET) is a molecular imaging technique that makes use of
radiolabelled molecules for in vivo evaluation. Carbon-11 is a frequently used radionuclide …
radiolabelled molecules for in vivo evaluation. Carbon-11 is a frequently used radionuclide …
[HTML][HTML] A randomized controlled study to evaluate the effect of bexarotene on amyloid-β and apolipoprotein E metabolism in healthy subjects
K Ghosal, M Haag, PB Verghese, T West… - Alzheimer's & Dementia …, 2016 - Elsevier
Introduction We conducted a phase Ib proof of mechanism trial to determine whether
bexarotene (Targretin) increases central nervous system (CNS) apolipoprotein E (apoE) …
bexarotene (Targretin) increases central nervous system (CNS) apolipoprotein E (apoE) …
Activation of RXR/PPARγ underlies neuroprotection by bexarotene in ischemic stroke
The identification of novel drug targets for the treatment of ischemic stroke is currently an
urgent challenge. Recent experimental findings have highlighted the neuroprotective …
urgent challenge. Recent experimental findings have highlighted the neuroprotective …
Boron reagents for divergent radiochemistry
TC Wilson, T Cailly, V Gouverneur - Chemical Society Reviews, 2018 - pubs.rsc.org
Radiolabelled (bio) molecules have advanced many areas of science from fundamental
biology to human health including applications in molecular imaging and more generally …
biology to human health including applications in molecular imaging and more generally …