[HTML][HTML] Overcoming cancer therapeutic bottleneck by drug repurposing
Ever present hurdles for the discovery of new drugs for cancer therapy have necessitated
the development of the alternative strategy of drug repurposing, the development of old …
the development of the alternative strategy of drug repurposing, the development of old …
[HTML][HTML] Molecular mechanisms of action of genistein in cancer: Recent advances
HS Tuli, MJ Tuorkey, F Thakral, K Sak… - Frontiers in …, 2019 - frontiersin.org
Background: Genistein is one among the several other known isoflavones that is found in
different soybeans and soy products. The chemical name of genistein is 4′, 5, 7 …
different soybeans and soy products. The chemical name of genistein is 4′, 5, 7 …
[HTML][HTML] Thymoquinone (2-Isopropyl-5-methyl-1, 4-benzoquinone) as a chemopreventive/anticancer agent: Chemistry and biological effects
Cancer remains the topmost disorder of the mankind and number of cases is unceasingly
growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the …
growing at unprecedented rates. Although the synthetic anti-cancer compounds still hold the …
Natural products for cancer therapy: a review of their mechanism of actions and toxicity in the past decade
YO Ali Abdalla, B Subramaniam… - Journal of Tropical …, 2022 - Wiley Online Library
The ethnopharmacological information gathered over many centuries and the presence of
diverse metabolites have made the medicinal plants as the prime source of drugs. Despite …
diverse metabolites have made the medicinal plants as the prime source of drugs. Despite …
Targeting PI3K/Akt signaling in prostate cancer therapy
M Hashemi, A Taheriazam, P Daneii… - Journal of Cell …, 2023 - Springer
Urological cancers have obtained much attention in recent years due to their mortality and
morbidity. The most common and malignant tumor of urological cancers is prostate cancer …
morbidity. The most common and malignant tumor of urological cancers is prostate cancer …
Therapeutic potentials of genistein: New insights and perspectives
Genistein, a polyphenolic isoflavone compound found abundantly in soy or soy‐based
products, is widely consumed in the Asian population. Genistein has poor bioavailability, to …
products, is widely consumed in the Asian population. Genistein has poor bioavailability, to …
[HTML][HTML] Inhibition of Cancer Development by Natural Plant Polyphenols: Molecular Mechanisms
A Lyubitelev, V Studitsky - International Journal of Molecular Sciences, 2023 - mdpi.com
Malignant tumors remain one of the main sources of morbidity and mortality around the
world. A chemotherapeutic approach to cancer treatment poses a multitude of challenges …
world. A chemotherapeutic approach to cancer treatment poses a multitude of challenges …
[HTML][HTML] Effects of flavonoids on cancer, cardiovascular and neurodegenerative diseases: Role of NF-κB signaling pathway
MM Barreca, R Alessandro, C Corrado - International Journal of …, 2023 - mdpi.com
Flavonoids are polyphenolic phytochemical compounds found in many plants, fruits,
vegetables, and leaves. They have a multitude of medicinal applications due to their anti …
vegetables, and leaves. They have a multitude of medicinal applications due to their anti …
[HTML][HTML] Anticancer effects of natural phytochemicals in anaplastic thyroid cancer
Y Li, J Zhang, H Zhou, Z Du - Oncology Reports, 2022 - spandidos-publications.com
Anaplastic thyroid cancer (ATC) is an aggressive and lethal malignancy having a dismal
prognosis. Phytochemicals are bioactive components obtained from plants that have been …
prognosis. Phytochemicals are bioactive components obtained from plants that have been …
Thymoquinone inhibits proliferation and migration of MDA-MB-231 triple negative breast cancer cells by suppressing autophagy, Beclin-1 and LC3
TD Ünal, Z Hamurcu, N Delibaşı, V Çınar… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
Background: Triple Negative Breast Cancer (TNBC) is an aggressive and highly
heterogeneous subtype of breast cancer associated with poor prognosis. A better …
heterogeneous subtype of breast cancer associated with poor prognosis. A better …