Objective We investigated the comparative efficacy and tolerability of pharmacological
treatment strategies for the treatment of acute bipolar depression. Data sources A systematic …

Objective: The role of antidepressants in the acute treatment of bipolar depression remains a
contentious issue. A previous meta-analysis of randomized controlled trials (RCTs) …

The Canadian Network for Mood and Anxiety Treatments (CANMAT) previously published
treatment guidelines for bipolar disorder in 2005, along with international commentaries and …

Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Beaulieu S, Alda M, O'Donovan C,
MacQueen G, McIntyre RS, Sharma V, Ravindran A, Young LT, Milev R, Bond DJ, Frey BN …

The British Association for Psychopharmacology guidelines specify the scope and targets of
treatment for bipolar disorder. The third version is based explicitly on the available evidence …

Objectives. These guidelines are based on a first edition that was published in 2002, and
have been edited and updated with the available scientific evidence until September 2009 …

Objective Few studies have been reported that support the efficacy of adjunctive therapy for
patients with bipolar I depression who have had an insufficient response to monotherapy …

Currently available antidepressants used to treat major depressive disorder (MDD)
unfortunately often take weeks to months to achieve their full effects, commonly resulting in …

Bipolar II disorder (recurrent depressive and hypomanic episodes) and related disorders
(united in the bipolar spectrum) are understudied, despite a prevalence of about 5% in the …

Berk M, Brnabic A, Dodd S, Kelin K, Tohen M, Malhi GS, Berk L, Conus P, McGorry PD. Does
stage of illness impact treatment response in bipolar disorder? Empirical treatment data and …