Ultra-processed foods and food additives in gut health and disease

K Whelan, AS Bancil, JO Lindsay… - Nature Reviews …, 2024 - nature.com
Ultra-processed foods (UPFs) and food additives have become ubiquitous components of
the modern human diet. There is increasing evidence of an association between diets rich in …

T cell dysfunction and therapeutic intervention in cancer

CC Zebley, D Zehn, S Gottshalk, H Chi - Nature Immunology, 2024 - nature.com
Recent advances in immunotherapy have affirmed the curative potential of T cell-based
approaches for treating relapsed and refractory cancers. However, the therapeutic efficacy is …

Nutrients: Signal 4 in T cell immunity

JL Raynor, H Chi - Journal of Experimental Medicine, 2024 - rupress.org
T cells are integral in mediating adaptive immunity to infection, autoimmunity, and cancer.
Upon immune challenge, T cells exit from a quiescent state, followed by clonal expansion …

Association of ultra-processed food consumption with all cause and cause specific mortality: population based cohort study

Z Fang, SL Rossato, D Hang, N Khandpur, K Wang… - bmj, 2024 - bmj.com
Objective To examine the association of ultra-processed food consumption with all cause
mortality and cause specific mortality. Design Population based cohort study. Setting Female …

Sucralose and Erythritol—Not Too Sweet

H Tilg, TE Adolph - New England Journal of Medicine, 2023 - Mass Medical Soc
Sucralose and Erythritol — Not Too Sweet | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Sugar-sweetened beverages and artificially sweetened beverages consumption and the risk of nonalcoholic fatty liver (NAFLD) and nonalcoholic steatohepatitis …

TS Tseng, WT Lin, PS Ting, CK Huang, PH Chen… - Nutrients, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) are fast
becoming the most common chronic liver disease and are often preventable with healthy …

Physiological Integration of Taste and Metabolism

JM Egan - New England Journal of Medicine, 2024 - Mass Medical Soc
Key Points Physiological Integration of Taste and Metabolism The tongue taste map that we
all learned in school is wrong; taste receptor cells responsive to each of the tastes are …

Artificial sweetener sucralose: a possible modulator of autoimmune diseases

N Kränkel, U Rauch-Kroehnert - Signal Transduction and Targeted …, 2023 - nature.com
In their research article in Nature in March 2023, Fabio Zani and colleagues reported that
high concentrations of the zero-calorie artificial sweetener sucralose affected the …

Acute intake of sucrose but not of the intense sweetener sucralose is associated with post-prandial endotoxemia in healthy young adults—a randomized controlled …

R Staltner, V Sánchez, I Bergheim, A Baumann - Nutrients, 2023 - mdpi.com
Sugar-rich diets, but also the use of intense sweeteners, may alter intestinal barrier function.
Here, we assessed the effect of sucrose and sucralose on post-prandial endotoxemia in a …

Long-term metabolic effects of non-nutritive sweeteners

M Rathaus, L Azem, R Livne, S Ron, I Ron, R Hadar… - Molecular …, 2024 - Elsevier
Objective Excessive consumption of added sugars has been linked to the rise in obesity and
associated metabolic abnormalities. Non-nutritive sweeteners (NNSs) offer a potential …