Single-cell transcriptomics reveals evidence of endothelial dysfunction in the brains of COVID-19 patients with implications for glioblastoma progression

A Thakur, L Liang, S Banerjee, K Zhang - Brain sciences, 2023 - mdpi.com
Background: Endothelial dysfunction is implicated in various inflammatory diseases such as
ischemic stroke, heart attack, organ failure, and COVID-19. Recent studies have shown that …

ARAP1-AS1: a novel long non-coding RNA with a vital regulatory role in human cancer development

J Wang, H Luo, L Yang, H Yuan - Cancer cell international, 2024 - Springer
Long non-coding RNAs (lncRNAs) have garnered significant attention in biomedical
research due to their pivotal roles in gene expression regulation and their association with …

[HTML][HTML] Chronic and acute exposure to rotenone reveals distinct Parkinson's disease-related phenotypes in human iPSC-derived peripheral neurons

MA Saleh, F Amer-Sarsour, A Berant… - Free Radical Biology …, 2024 - Elsevier
Peripheral autonomic nervous system (P-ANS) dysfunction is a critical non-motor phenotype
of Parkinson's disease (PD). The majority of PD cases are sporadic and lack identified PD …

Long Intergenic Non-Coding RNAs of Human Chromosome 18: Focus on Cancers

PV Ershov, EO Yablokov, YV Mezentsev, AS Ivanov - Biomedicines, 2024 - mdpi.com
Malignant neoplasms are characterized by high molecular heterogeneity due to multilevel
deregulation of gene expression and cellular functions. It is known that non-coding RNAs …

The effect of race/ethnicity and MED12 mutation on the expression of long non-coding RNAs in uterine leiomyoma and myometrium

TD Chuang, N Ton, S Rysling, D Boos… - International journal of …, 2024 - mdpi.com
The objective of this study was to elucidate the expression of long non-coding RNA
(lncRNA) in leiomyomas (Lyo) and paired myometrium (Myo) and explore the impact of race …

[HTML][HTML] Evaluation of the expression level of some coding and non-coding genes in oral squamous cell carcinoma

M Ajorlou, P Bina-Jourshari, S Mirzaei… - Molecular and cellular …, 2023 - Elsevier
Introduction Oral squamous cell carcinoma (OSCC) is the most common cancers arising
from the head and neck region. There is growing evidence that lncRNAs play an important …

Whole-blood RNA biomarkers for predicting survival in non-human primates following thoracic radiation

MJ Aryankalayil, H Patel, JM May, U Shankavaram… - Scientific Reports, 2024 - nature.com
Radiation injury, either from radiotherapy or a mass-casualty event requires a health care
system that can efficiently allocate resources to patients. We conducted a comprehensive …

Differential expression of angiogenesis-related genes 'VEGF'and 'angiopoietin-1'in metastatic and EMAST-positive colorectal cancer patients

A Torshizi Esfahani, S Mohammadpour, P Jalali… - Scientific Reports, 2024 - nature.com
Abnormal angiogenesis leads to tumor progression and metastasis in colorectal cancer
(CRC). This study aimed to elucidate the association between angiogenesis-related genes …

Laryngeal cancer diagnosis via miRNA-based decision tree model

A Arora, IF Tsigelny, VL Kouznetsova - European Archives of Oto-Rhino …, 2024 - Springer
Purpose Laryngeal cancer (LC) is the most common head and neck cancer, which often
goes undiagnosed due to the inaccessible nature of current diagnosis methods in some …

Discriminatory power of a circulating multi-noncoding RNA panel in acute coronary syndrome subtypes: Towards precision detection

SHA Agwa, SS Elzahwy, N Hossam, YA Yahia… - … International Journal of …, 2024 - Elsevier
Abstract Background Acute Coronary Syndrome (ACS) stands as a significant contributor to
cardiovascular mortality, necessitating improved diagnostic tools for early detection and …