Biosimilars in ophthalmology:“Is there a big change on the horizon?”

A Sharma, P Reddy, BD Kuppermann… - Clinical …, 2018 - Taylor & Francis
Retinal disease management has witnessed remarkable advances in posterior segment
pharmacotherapy with the development of anti-VEGF molecules such as Lucentis® …

Biosimilars for retinal diseases: an update

A Sharma, N Kumar, N Parachuri, F Bandello… - American journal of …, 2021 - Elsevier
Purpose To review the biosimilars of anti–vascular endothelial growth factor agents for
retinal diseases and provide an update about their development. Design Literature review …

Anti-VEGF and other novel therapies for neovascular age-related macular degeneration: an update

M Parravano, E Costanzo, G Scondotto, G Trifirò… - BioDrugs, 2021 - Springer
Age-related macular degeneration (AMD) is a leading cause of visual impairment and
blindness in older adults. The prognosis for the neovascular type of advanced AMD …

The state-of-the-art pharmacotherapeutic management of neovascular age-related macular degeneration

A Servillo, I Zucchiatti, R Sacconi… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Age-related macular degeneration (AMD) is a major cause of central visual loss
in the developed world. Although the pathogenesis is not fully understood, vascular …

Current and novel therapeutic approaches for treatment of diabetic macular edema

MZ Chauhan, PA Rather, SM Samarah, AM Elhusseiny… - Cells, 2022 - mdpi.com
Diabetic macular edema (DME) is a major ocular complication of diabetes mellitus (DM),
leading to significant visual impairment. DME's pathogenesis is multifactorial. Focal edema …

Macular neovascularization

JU Sheth, MW Stewart, R Narayanan… - Survey of …, 2024 - Elsevier
Neovascularization of the macula, a common complication of many chorioretinal diseases
such as neovascular age-related macular degeneration, polypoidal choroidal vasculopathy …

Changing trends in the use of anti-vascular endothelial growth factor (anti-VEGF) biosimilars: insights from the Vitreoretinal Society of India Biosimilars of Anti-VEGF …

JU Sheth, MW Stewart, M Khatri, SR Gupta… - Indian Journal of …, 2021 - journals.lww.com
Purpose: The aim of this study was to present the outcomes of the 2018 and 2020 Vitreo-
retinal Society of India (VRSI) biosimilars of anti-vascular endothelial growth factor …

Understanding biosimilars and its regulatory aspects across the globe: an ophthalmology perspective

A Sharma, N Kumar, BD Kuppermann… - British Journal of …, 2020 - bjo.bmj.com
Purpose This article aims to analyse the key regulatory guidelines across the globe
concerning biosimilars. Materials and methods Review of the current literature. Results …

Real-world outcomes with ranibizumab in branch retinal vein occlusion: The prospective, global, LUMINOUS study

I Pearce, A Clemens, MH Brent, L Lu… - PLoS …, 2020 - journals.plos.org
Objective To evaluate the effectiveness, safety, and treatment patterns of ranibizumab 0.5
mg in treatment-naïve patients with branch retinal vein occlusion (BRVO) enrolled in the …

A multicenter, retrospective study (RE-ENACT 2) on the use of Razumab™(world's first biosimilar ranibizumab) in wet age-related macular degeneration

S Sharma, M Khan, A Chaturvedi… - Ophthalmology and …, 2020 - Springer
Abstract Introduction The REal life assessmENt of safety And effeCTiveness of Razumab
(RE-ENACT) and long-term RE-ENACT 2 retrospective studies have evaluated the use of …