The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …

Objective. Corneal neovascularization is a sight-threatening condition affecting more than
1.4 million people per year. Left untreated, it can lead to tissue scarring, oedema, lipid …

MicroRNAs are non-coding RNAs that serve as regulatory molecules in a variety of
pathways such as inflammation, metabolism, homeostasis, cell machinery, and …

Herpes simplex virus type-1 (HSV-1) is a ubiquitous pathogen that infects a large majority of
the human population worldwide. It is also a leading cause of infection-related blindness in …

Herpes stromal keratitis (HSK) is one of the primary diseases that cause vision loss or even
blindness after herpes simplex virus (HSV)-1 infection. HSK-associated vision impairment is …

HSV-1 infection of the cornea leads to a blinding immunoinflammatory lesion of the eye
termed stromal keratitis (SK). Recently, IL-17–producing CD4+ T cells (Th17 cells) were …

Several viruses are recognized as the direct or indirect causative agents of human tumors
and other severe human diseases. Vascular endothelial growth factor (VEGF) is identified as …

Herpes simplex virus type 1 (HSV-1) is a highly successful pathogen that primarily infects
epithelial cells of the orofacial mucosa. After initial lytic replication, HSV-1 enters sensory …

The cornea actively maintains its own avascular status to preserve its ultimate optical
function. This corneal avascular state is also defined as “corneal angiogenic privilege” …

MicroRNAs (miRNAs) are small regulatory molecules that control diverse biological
processes that include angiogenesis. Herpes simplex virus (HSV) causes a chronic immuno …