Application of 1, 2, 4-triazolo [1, 5-a] pyrimidines for the design of coordination compounds with interesting structures and new biological properties
I Łakomska, M Fandzloch - Coordination Chemistry Reviews, 2016 - Elsevier
This article reviews investigations conducted over the last 15 years that aimed to develop
coordination compounds with 1, 2, 4-triazolo [1, 5-a] pyrimidines. The rich diversity of this …
coordination compounds with 1, 2, 4-triazolo [1, 5-a] pyrimidines. The rich diversity of this …
Recent advances in 1, 2, 4-triazolo [1, 5-a] pyrimidine chemistry
G Fischer - Advances in Heterocyclic Chemistry, 2019 - Elsevier
The review deals with the pharmaceutically and agrochemically important group of 1, 2, 4-
triazolo [1, 5-a] pyrimidines (TPs) and covers relevant literature published from about 2006 …
triazolo [1, 5-a] pyrimidines (TPs) and covers relevant literature published from about 2006 …
Searching for new chemotherapies for tropical diseases: Ruthenium–clotrimazole complexes display high in vitro activity against Leishmania major and Trypanosoma …
A Martínez, T Carreon, E Iniguez… - Journal of medicinal …, 2012 - ACS Publications
Eight new ruthenium complexes of clotrimazole (CTZ) with high antiparasitic activity have
been synthesized, cis, fac-[RuIICl2 (DMSO) 3 (CTZ)](1), cis, cis, trans-[RuIICl2 (DMSO) 2 …
been synthesized, cis, fac-[RuIICl2 (DMSO) 3 (CTZ)](1), cis, cis, trans-[RuIICl2 (DMSO) 2 …
Triazolopyrimidine compounds containing first-row transition metals and their activity against the neglected infectious Chagas disease and leishmaniasis
AB Caballero, A Rodríguez-Diéguez, M Quirós… - European journal of …, 2014 - Elsevier
Leishmaniasis and Chagas disease remain a significant global problem. Current treatments
have serious disadvantage due to cost, toxicity, long therapy duration and resistance. In the …
have serious disadvantage due to cost, toxicity, long therapy duration and resistance. In the …
An exhaustive compilation on chemistry of triazolopyrimidine: A journey through decades
The triazolopyrimidine scaffold represents one of the privileged structure in chemistry, and
there has been an increase in number of studies utilizing this scaffold and its derivatives …
there has been an increase in number of studies utilizing this scaffold and its derivatives …
New oxidovanadium (IV) N-acylhydrazone complexes: Promising antileishmanial and antitrypanosomal agents
Searching for new promising metal-based hits against Trypanosoma cruzi and Leishmania
parasites, two related oxidovanadium (IV) N-acylhydrazone complexes,[VIVO …
parasites, two related oxidovanadium (IV) N-acylhydrazone complexes,[VIVO …
Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1, 4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit …
The limited efficacy of benznidazole (Bz) indicated by failures of current Phase II clinical
trials emphasizes the urgent need to identify new drugs with improved safety and efficacy for …
trials emphasizes the urgent need to identify new drugs with improved safety and efficacy for …
[HTML][HTML] Cytotoxic activity of organotin (IV) derivatives with triazolopyrimidine containing exocyclic oxygen atoms
A Attanzio, S D'Agostino, R Busà, A Frazzitta, S Rubino… - Molecules, 2020 - mdpi.com
In this study cytotoxicity of organotin (IV) compounds with 1, 2, 4-triazolo [1, 5-a] pyrimidines,
Me3Sn (5tpO)(1), n-Bu3Sn (5tpO)(2), Me3Sn (mtpO)(3), n-Bu3Sn (mtpO)(4), n-Bu3Sn …
Me3Sn (5tpO)(1), n-Bu3Sn (5tpO)(2), Me3Sn (mtpO)(3), n-Bu3Sn (mtpO)(4), n-Bu3Sn …
In vitro leishmanicidal and trypanocidal evaluation and magnetic properties of 7-amino-1, 2, 4-triazolo [1, 5-a] pyrimidine Cu (II) complexes
Two triazolopyrimidine complexes have been obtained from reaction between 7-amino-1, 2,
4-triazolo [1, 5-a] pyrimidine (7atp) and Cu (II) salts. Crystal structures of [Cu 2 (μ-7atp) 4 Cl …
4-triazolo [1, 5-a] pyrimidine (7atp) and Cu (II) salts. Crystal structures of [Cu 2 (μ-7atp) 4 Cl …
In vitro anti-leishmania evaluation of nickel complexes with a triazolopyrimidine derivative against Leishmania infantum and Leishmania braziliensis
Studies on the anti-proliferative activity in vitro of seven ternary nickel (II) complexes with a
triazolopyrimidine derivative and different aliphatic or aromatic amines as auxiliary ligands …
triazolopyrimidine derivative and different aliphatic or aromatic amines as auxiliary ligands …