New pyranopyrazole based derivatives: Design, synthesis, and biological evaluation as potential topoisomerase II inhibitors, apoptotic inducers, and antiproliferative …

EA Sobh, AE Kassab, EA El-Khouly, MSA Hassan - Bioorganic Chemistry, 2024 - Elsevier
A new series of pyranopyrazole-based derivatives were designed and synthesized. The
synthesized compounds were assessed for their cytotoxic efficacy against A549 human lung …

Synthesis, Biological Evaluation, Molecular Docking, and Acid Dissociation Constant of New Bis‐1, 2, 3‐triazole Compounds

Y Nural, S Ozdemir, MS Yalcin, B Demir… - …, 2021 - Wiley Online Library
In this study, new bis‐1, 2, 3‐triazole derivatives, N, N′‐(1, 3‐phenylene) bis (2‐(4‐R‐1H‐
1, 2, 3‐triazol‐1‐yl) acetamide), were synthesized by copper‐catalyzed azide‐alkyne …