The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas
XY Fu-Shin, PSY Lee, L Yang, N Gao, Y Zhang… - Progress in retinal and …, 2022 - Elsevier
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …
several underlying pathophysiological mechanisms, some of which are still uncertain. The …
Corneal nerves in health and disease
BS Shaheen, M Bakir, S Jain - Survey of ophthalmology, 2014 - Elsevier
Corneal nerves are responsible for the sensations of touch, pain, and temperature and play
an important role in the blink reflex, wound healing, and tear production and secretion …
an important role in the blink reflex, wound healing, and tear production and secretion …
[HTML][HTML] A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells
Purpose Single cell (sc) analyses of key embryonic, fetal and adult stages were performed to
generate a comprehensive single cell atlas of all the corneal and adjacent conjunctival cell …
generate a comprehensive single cell atlas of all the corneal and adjacent conjunctival cell …
Global consensus on the management of limbal stem cell deficiency
Purpose: In recent decades, the medical and surgical treatment of limbal stem cell deficiency
(LSCD) has evolved significantly through the incorporation of innovative pharmacological …
(LSCD) has evolved significantly through the incorporation of innovative pharmacological …
Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation
In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …
their important roles in the maintenance of nerves in both homeostasis and inflammation …
Nerve dependence in tissue, organ, and appendage regeneration
A Kumar, JP Brockes - Trends in neurosciences, 2012 - cell.com
Many regeneration contexts require the presence of regenerating nerves as a transient
component of the progenitor cell niche. Here we review nerve involvement in regeneration …
component of the progenitor cell niche. Here we review nerve involvement in regeneration …
Understanding the pathogenesis of neurotrophic keratitis: the role of corneal nerves
L Mastropasqua, G Massaro‐Giordano… - Journal of cellular …, 2017 - Wiley Online Library
Neurotrophic keratitis (NK) is a rare degenerative disease of the cornea caused by
trigeminal nerve damage, which leads to loss of corneal sensitivity, corneal epithelium …
trigeminal nerve damage, which leads to loss of corneal sensitivity, corneal epithelium …
Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions
L Latta, FC Figueiredo, R Ashery-Padan, JM Collinson… - The ocular …, 2021 - Elsevier
Aniridia, a rare congenital disease, is often characterized by a progressive, pronounced
limbal insufficiency and ocular surface pathology termed aniridia-associated keratopathy …
limbal insufficiency and ocular surface pathology termed aniridia-associated keratopathy …
Salivary glands regenerate after radiation injury through SOX2‐mediated secretory cell replacement
E Emmerson, AJ May, L Berthoin… - EMBO molecular …, 2018 - embopress.org
Salivary gland acinar cells are routinely destroyed during radiation treatment for head and
neck cancer that results in a lifetime of hyposalivation and co‐morbidities. A potential …
neck cancer that results in a lifetime of hyposalivation and co‐morbidities. A potential …
Restoration of corneal sensation with regional nerve transfers and nerve grafts: a new approach to a difficult problem
U Elbaz, R Bains, RM Zuker, GH Borschel… - JAMA …, 2014 - jamanetwork.com
Importance Corneal anesthesia is recalcitrant to conventional treatment and can lead to
permanent visual loss. Objective To assess the outcomes of a novel sensory reconstructive …
permanent visual loss. Objective To assess the outcomes of a novel sensory reconstructive …