Machine learning techniques for personalised medicine approaches in immune-mediated chronic inflammatory diseases: applications and challenges
In the past decade, the emergence of machine learning (ML) applications has led to
significant advances towards implementation of personalised medicine approaches for …
significant advances towards implementation of personalised medicine approaches for …
Artificial intelligence and machine learning approaches using gene expression and variant data for personalized medicine
S Vadapalli, H Abdelhalim, S Zeeshan… - Briefings in …, 2022 - academic.oup.com
Precision medicine uses genetic, environmental and lifestyle factors to more accurately
diagnose and treat disease in specific groups of patients, and it is considered one of the …
diagnose and treat disease in specific groups of patients, and it is considered one of the …
The pathogenesis of systemic lupus erythematosus: harnessing big data to understand the molecular basis of lupus
MD Catalina, KA Owen, AC Labonte, AC Grammer… - Journal of …, 2020 - Elsevier
Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease that causes
damage to multiple organ systems. Despite decades of research and available murine …
damage to multiple organ systems. Despite decades of research and available murine …
Discovering biomarkers associated and predicting cardiovascular disease with high accuracy using a novel nexus of machine learning techniques for precision …
Personalized interventions are deemed vital given the intricate characteristics,
advancement, inherent genetic composition, and diversity of cardiovascular diseases …
advancement, inherent genetic composition, and diversity of cardiovascular diseases …
Re-focusing explainability in medicine
L Arbelaez Ossa, G Starke, G Lorenzini… - Digital …, 2022 - journals.sagepub.com
Using artificial intelligence to improve patient care is a cutting-edge methodology, but its
implementation in clinical routine has been limited due to significant concerns about …
implementation in clinical routine has been limited due to significant concerns about …
An introduction to machine learning and analysis of its use in rheumatic diseases
KM Kingsmore, CE Puglisi, AC Grammer… - Nature Reviews …, 2021 - nature.com
Abstract Machine learning (ML) is a computerized analytical technique that is being
increasingly employed in biomedicine. ML often provides an advantage over explicitly …
increasingly employed in biomedicine. ML often provides an advantage over explicitly …
Lupus or not? SLE Risk Probability Index (SLERPI): a simple, clinician-friendly machine learning-based model to assist the diagnosis of systemic lupus erythematosus
C Adamichou, I Genitsaridi, D Nikolopoulos… - Annals of the …, 2021 - ard.bmj.com
Objectives Diagnostic reasoning in systemic lupus erythematosus (SLE) is a complex
process reflecting the probability of disease at a given timepoint against competing …
process reflecting the probability of disease at a given timepoint against competing …
Drug repurposing to improve treatment of rheumatic autoimmune inflammatory diseases
The past century has been characterized by intensive efforts, within both academia and the
pharmaceutical industry, to introduce new treatments to individuals with rheumatic …
pharmaceutical industry, to introduce new treatments to individuals with rheumatic …
Leveraging heterogeneity in systemic lupus erythematosus for new therapies
Systemic lupus erythematosus (SLE) is a multisystem, chronic autoimmune disease where
treatment varies by patient and disease activity. Strong preclinical results and clinical …
treatment varies by patient and disease activity. Strong preclinical results and clinical …
Deep learning classification of systemic sclerosis skin using the MobileNetV2 model
Goal: Systemic sclerosis (SSc) is a rare autoimmune, systemic disease with prominent
fibrosis of skin and internal organs. Early diagnosis of the disease is crucial for designing …
fibrosis of skin and internal organs. Early diagnosis of the disease is crucial for designing …