[HTML][HTML] The PANcreatic Disease ReseArch (PANDoRA) consortium: ten years' experience of association studies to understand the genetic architecture of pancreatic …
D Campa, M Gentiluomo, A Stein, MN Aoki… - Critical Reviews in …, 2023 - Elsevier
Pancreatic cancer has an incidence that almost matches its mortality. Only a small number of
risk factors and 33 susceptibility loci have been identified. so Moreover, the relative rarity of …
risk factors and 33 susceptibility loci have been identified. so Moreover, the relative rarity of …
The long non-coding RNA ANRIL in cancers
A Sanchez, J Lhuillier, G Grosjean, L Ayadi, S Maenner - Cancers, 2023 - mdpi.com
Simple Summary The human genome produces various types of RNA molecules. A
significant portion of these are long non-coding RNAs (lncRNAs) exceeding 200 nts without …
significant portion of these are long non-coding RNAs (lncRNAs) exceeding 200 nts without …
[HTML][HTML] Genetic and non-genetic risk factors for early-onset pancreatic cancer
Y Nodari, M Gentiluomo… - Digestive and Liver …, 2023 - Elsevier
Background Early-onset pancreatic cancer (EOPC) represents 5–10% of all pancreatic
ductal adenocarcinoma (PDAC) cases, and the etiology of this form is poorly understood. It …
ductal adenocarcinoma (PDAC) cases, and the etiology of this form is poorly understood. It …
Interactive effects of CDKN2B‐AS1 gene polymorphism and habitual risk factors on oral cancer
JC Yeh, YT Chen, YE Chou, SC Su… - Journal of cellular …, 2023 - Wiley Online Library
Oral squamous cell carcinoma (OSCC) is a common malignant disease associated with a
high mortality rate and heterogeneous disease aetiology. Cyclin dependent kinase inhibitor …
high mortality rate and heterogeneous disease aetiology. Cyclin dependent kinase inhibitor …
Polymorphic variants involved in methylation regulation: a strategy to discover risk loci for pancreatic ductal adenocarcinoma
C Corradi, G Lencioni, M Gentiluomo, A Felici… - Journal of medical …, 2023 - jmg.bmj.com
Introduction Only a small number of risk factors for pancreatic ductal adenocarcinoma
(PDAC) has been established. Several studies identified a role of epigenetics and of …
(PDAC) has been established. Several studies identified a role of epigenetics and of …
The intergenic type LncRNA (LINC RNA) faces in cancer with in silico scope and a directed lens to LINC00511: a step toward ncRNA precision
Background: Long intergenic non-coding RNA, is one type of lncRNA, exerting various
cellular activities, as does ncRNA, including the regulation of gene expression and …
cellular activities, as does ncRNA, including the regulation of gene expression and …
Role of pancreatic ductal adenocarcinoma risk factors in intraductal papillary mucinous neoplasm progression
M Gentiluomo, C Corradi, PG Arcidiacono… - Frontiers in …, 2023 - frontiersin.org
Introduction Pancreatic ductal adenocarcinoma (PDAC) is lethal due to its late diagnosis
and lack of successful treatments. A possible strategy to reduce its death burden is …
and lack of successful treatments. A possible strategy to reduce its death burden is …
[HTML][HTML] Analysis of exposome and genetic variability suggests stress as a major contributor for development of pancreatic ductal adenocarcinoma
Background The current knowledge on pancreatic ductal adenocarcinoma (PDAC) risk
factors is limited and no study has comprehensively tested the exposome in combination …
factors is limited and no study has comprehensively tested the exposome in combination …
Long or short? Telomere length and pancreatic cancer and its precursor lesions, a narrative review
D Campa, A Felici, C Corradi, G Peduzzi… - …, 2023 - academic.oup.com
Pancreatic ductal adenocarcinoma (PDAC) is the most common and lethal form of
pancreatic cancer, with a survival approaching only 11% at five years after diagnosis. In the …
pancreatic cancer, with a survival approaching only 11% at five years after diagnosis. In the …
Explainable machine learning identifies a polygenic risk score as a key predictor of pancreatic cancer risk in the UK Biobank
G Peduzzi, A Felici, R Pellungrini, D Campa - Digestive and Liver Disease, 2024 - Elsevier
Background Predicting the risk of developing pancreatic ductal adenocarcinoma (PDAC) is
of paramount importance, given its high mortality rate. Current PDAC risk prediction models …
of paramount importance, given its high mortality rate. Current PDAC risk prediction models …