Microfluidic single-cell manipulation and analysis: Methods and applications
In a forest of a hundred thousand trees, no two leaves are alike. Similarly, no two cells in a
genetically identical group are the same. This heterogeneity at the single-cell level has been …
genetically identical group are the same. This heterogeneity at the single-cell level has been …
Microfluidic single‐cell omics analysis
The commonly existing cellular heterogeneity plays a critical role in biological processes
such as embryonic development, cell differentiation, and disease progress. Single‐cell …
such as embryonic development, cell differentiation, and disease progress. Single‐cell …
Detection of prostate specific antigen in whole blood by microfluidic chip integrated with dielectrophoretic separation and electrochemical sensing
X Wang, X He, Z He, L Hou, C Ge, L Wang, S Li… - Biosensors and …, 2022 - Elsevier
The efficient detection of cancer markers has faced many challenges, such as severe
interference, complicated and time-consuming operation, low sensitivity and so on. In this …
interference, complicated and time-consuming operation, low sensitivity and so on. In this …
The revolution of PDMS microfluidics in cellular biology
S Banik, A Uchil, T Kalsang, S Chakrabarty… - Critical Reviews in …, 2023 - Taylor & Francis
Microfluidics is revolutionizing the way research on cellular biology has been traditionally
conducted. The ability to control the cell physicochemical environment by adjusting flow …
conducted. The ability to control the cell physicochemical environment by adjusting flow …
High-throughput separation, trapping, and manipulation of single cells and particles by combined dielectrophoresis at a bipolar electrode array
Microfluidic systems have been developed widely in scaled-down processes of laboratory
techniques, but they are usually limited in achieving stand-alone functionalities. It is highly …
techniques, but they are usually limited in achieving stand-alone functionalities. It is highly …
Microfluidic single-cell transcriptomics: moving towards multimodal and spatiotemporal omics
Cells are the basic units of life with vast heterogeneity. Single-cell transcriptomics unveils
cell-to-cell gene expression variabilities, discovers novel cell types, and uncovers the critical …
cell-to-cell gene expression variabilities, discovers novel cell types, and uncovers the critical …
Recent progress of microfluidic technology for pharmaceutical analysis
X Jia, X Yang, G Luo, Q Liang - Journal of Pharmaceutical and Biomedical …, 2022 - Elsevier
In recent years, the progress of microfluidic technology has provided new tools for
pharmaceutical analysis and the proposal of pharm-lab-on-a-chip is appealing for its great …
pharmaceutical analysis and the proposal of pharm-lab-on-a-chip is appealing for its great …
[HTML][HTML] Single-cell assay on microfluidic devices
Advances in microfluidic techniques have prompted researchers to study the inherent
heterogeneity of single cells in cell populations. This would be helpful in the identification of …
heterogeneity of single cells in cell populations. This would be helpful in the identification of …
Microfluidic device embedding electrodes for dielectrophoretic manipulation of cells‐A review
Microfluidic device embedding electrodes realizes cell manipulation with the help of
dielectrophoresis. Cell manipulation is an important technology for cell sorting and cell …
dielectrophoresis. Cell manipulation is an important technology for cell sorting and cell …
Microfluidics coupled mass spectrometry for single cell multi‐omics
D Zhang, L Qiao - Small Methods, 2024 - Wiley Online Library
Population‐level analysis masks significant heterogeneity between individual cells, making
it difficult to accurately reflect the true intricacies of life activities. Microfluidics is a technique …
it difficult to accurately reflect the true intricacies of life activities. Microfluidics is a technique …