Transition metal-catalyzed direct functionalization of C–H bonds is one of the key emerging
strategies that is currently attracting tremendous attention with the aim to provide alternative …

C− C bond formation is a fundamental transformation in organic synthesis. The development
of new synthetic methodology could be considered as a way of pursuing a novel method for …

The catalytic functionalization of unreactive C− H bonds has recently brought a revolution in
synthetic methodologies for the production of pharmaceuticals and natural products and for …

Synthetically useful functional groups, including ketones, amides, carbamates, carboxylic
acids, aldehydes or ethers, have been identified as weakly coordinating directing groups in …

The transition metal-catalyzed transformation of otherwise inert C–H bonds into substituted
alkenes offers a versatile tool for the synthesis of value added olefinic molecules. Recent …

Significant progress has been accomplished in direct olefinations through twofold C–H bond
functionalization of arenes and heteroarenes employing readily accessible, selective and …

Pd-catalyzed C–H functionalizations promoted by transient directing groups remain largely
limited to C–H arylation only. Herein, we report a diverse set of ortho-C (sp2)–H …

Ruthenium catalysts enabled C–H bond functionalizations on arenes with challenging
secondary alkyl halides. Particularly, ruthenium (II) biscarboxylate complexes proved to be …

The transition-metal-catalyzed chelation-assisted alkenylation at the inert C–H bond of
aromatics with alkenes is one of the efficient methods to synthesize substituted vinylarenes …

Palladium-catalyzed coupling between aryl halides and alkenes (Mizoroki–Heck reaction) is
one of the most popular reactions for synthesizing complex organic molecules. The limited …