Isolated growth hormone deficiency (GHD) in childhood and adolescence: recent advances
KS Alatzoglou, EA Webb, P Le Tissier… - Endocrine …, 2014 - academic.oup.com
The diagnosis of GH deficiency (GHD) in childhood is a multistep process involving clinical
history, examination with detailed auxology, biochemical testing, and pituitary imaging, with …
history, examination with detailed auxology, biochemical testing, and pituitary imaging, with …
[HTML][HTML] Anterior pituitary cell networks
PR Le Tissier, DJ Hodson, C Lafont… - Frontiers in …, 2012 - Elsevier
Both endocrine and non-endocrine cells of the pituitary gland are organized into structural
and functional networks which are formed during embryonic development but which may be …
and functional networks which are formed during embryonic development but which may be …
An updated view of hypothalamic–vascular–pituitary unit function and plasticity
The discoveries of novel functional adaptations of the hypothalamus and anterior pituitary
gland for physiological regulation have transformed our understanding of their interaction …
gland for physiological regulation have transformed our understanding of their interaction …
[HTML][HTML] Existence of long-lasting experience-dependent plasticity in endocrine cell networks
Experience-dependent plasticity of cell and tissue function is critical for survival by allowing
organisms to dynamically adjust physiological processes in response to changing or harsh …
organisms to dynamically adjust physiological processes in response to changing or harsh …
A tridimensional view of pituitary development and function
Recent advances in tridimensional (3D) tissue imaging have considerably enriched our view
of the pituitary gland and its development. Whereas traditional histology of the pituitary …
of the pituitary gland and its development. Whereas traditional histology of the pituitary …
Development of the pituitary gland
KS Alatzoglou, LC Gregory… - Comprehensive …, 2020 - discovery.ucl.ac.uk
The development of the anterior pituitary gland occurs in distinct sequential developmental
steps, leading to the formation of a complex organ containing five different cell types …
steps, leading to the formation of a complex organ containing five different cell types …
[HTML][HTML] Functional pituitary networks in vertebrates
Y Santiago-Andres, M Golan… - Frontiers in Endocrinology, 2021 - frontiersin.org
The pituitary is a master endocrine gland that developed early in vertebrate evolution and
therefore exists in all modern vertebrate classes. The last decade has transformed our view …
therefore exists in all modern vertebrate classes. The last decade has transformed our view …
A new perspective on regulation of pituitary plasticity: the network of SOX2-positive cells may coordinate responses to challenge
PR Le Tissier, JF Murray, P Mollard - Endocrinology, 2022 - academic.oup.com
Plasticity of function is required for each of the anterior pituitary endocrine axes to support
alterations in the demand for hormone with physiological status and in response to …
alterations in the demand for hormone with physiological status and in response to …
[HTML][HTML] Anatomical and functional gonadotrope networks in the teleost pituitary
M Golan, AO Martin, P Mollard, B Levavi-Sivan - Scientific reports, 2016 - nature.com
Mammalian pituitaries exhibit a high degree of intercellular coordination; this enables them
to mount large-scale coordinated responses to various physiological stimuli. This type of …
to mount large-scale coordinated responses to various physiological stimuli. This type of …
Plasticity of the prolactin (PRL) axis: mechanisms underlying regulation of output in female mice
PR Le Tissier, DJ Hodson, AO Martin… - Recent Advances in …, 2015 - Springer
The output of prolactin (PRL) is highly dynamic with dramatic changes in its secretion from
the anterior pituitary gland depending on prevailing physiological status. In adult female …
the anterior pituitary gland depending on prevailing physiological status. In adult female …