Molecular ratchets and kinetic asymmetry: Giving chemistry direction

S Borsley, DA Leigh… - Angewandte Chemie …, 2024 - Wiley Online Library
Over the last two decades ratchet mechanisms have transformed the understanding and
design of stochastic molecular systems—biological, chemical and physical—in a move away …

Bio-inspired molecular machines and their biological applications

MN Tasbas, E Sahin, S Erbas-Cakmak - Coordination Chemistry Reviews, 2021 - Elsevier
Molecular machines lie at the center of living systems by taking a role in all fundamental
processes that constitute life including cell division, cellular trafficking, and macromolecule …

Light-activated molecular machines are fast-acting broad-spectrum antibacterials that target the membrane

AL Santos, D Liu, AK Reed, AM Wyderka… - Science …, 2022 - science.org
The increasing occurrence of antibiotic-resistant bacteria and the dwindling antibiotic
research and development pipeline have created a pressing global health crisis. Here, we …

Bottom-up: can supramolecular tools deliver responsiveness from molecular motors to macroscopic materials?

Q Zhang, DH Qu, H Tian, BL Feringa - Matter, 2020 - cell.com
Motion is omnipresent, as is obvious from the artificial machines in the macro-world and the
biomolecular motors in living systems, controlling dynamic behavior along many length …

Active mechanical threading by a molecular motor

NN Bach, V Josef, H Maid… - Angewandte Chemie …, 2022 - Wiley Online Library
Molecular motors transform external energy input into directional motions and offer exquisite
precision for nano‐scale manipulations. To make full use of molecular motor capacities, their …

Molecular machines stimulate intercellular calcium waves and cause muscle contraction

JL Beckham, AR van Venrooy, S Kim, G Li, B Li… - Nature …, 2023 - nature.com
Intercellular calcium waves (ICW) are complex signalling phenomena that control many
essential biological activities, including smooth muscle contraction, vesicle secretion, gene …

Nonlethal Molecular Nanomachines Potentiate Antibiotic Activity Against Gram-Negative Bacteria by Increasing Cell Permeability and Attenuating Efflux

AL Santos, D Liu, A van Venrooy, JL Beckham… - ACS …, 2024 - ACS Publications
Antibiotic resistance is a pressing public health threat. Despite rising resistance, antibiotic
development, especially for Gram-negative bacteria, has stagnated. As the traditional …

Steric effects on the thermal processes of hemithioindigo based molecular motor rotation

LA Huber, S Thumser, K Grill, D Voßiek… - … A European Journal, 2021 - Wiley Online Library
Tuning the thermal behavior of light driven molecular motors is fundamentally important for
their future rational design. In many molecular motors thermal ratcheting steps are …

Accounts of applied molecular rotors and rotary motors: recent advances

A Singhania, S Kalita, P Chettri, S Ghosh - Nanoscale Advances, 2023 - pubs.rsc.org
Molecular machines are nanoscale devices capable of performing mechanical works at
molecular level. These systems could be a single molecule or a collection of component …

Impact of solvation on the photoisomerisation dynamics of a photon-only rotary molecular motor

M Filatov, M Paolino, D Kaliakin, M Olivucci… - Communications …, 2024 - nature.com
The optimization of the quantum efficiency of single-molecule light-driven rotary motors
typically relies on chemical modifications. While, in isolated conditions, computational …