[HTML][HTML] Quantification of brain oxygen extraction and metabolism with [15O]-gas PET: A technical review in the era of PET/MRI
Oxygen extraction fraction (OEF) and the cerebral metabolic rate of oxygen (CMRO 2) are
key cerebral physiological parameters to identify at-risk cerebrovascular patients and …
key cerebral physiological parameters to identify at-risk cerebrovascular patients and …
An update on the use of image-derived input functions for human PET studies: new hopes or old illusions?
Background The need for arterial blood data in quantitative PET research limits the wider
usability of this imaging method in clinical research settings. Image-derived input function …
usability of this imaging method in clinical research settings. Image-derived input function …
Long-delay arterial spin labeling provides more accurate cerebral blood flow measurements in moyamoya patients: a simultaneous positron emission tomography …
Background and Purpose—Arterial spin labeling (ASL) MRI is a promising, noninvasive
technique to image cerebral blood flow (CBF) but is difficult to use in cerebrovascular …
technique to image cerebral blood flow (CBF) but is difficult to use in cerebrovascular …
[HTML][HTML] Cerebrovascular reactivity measurements using simultaneous 15O-water PET and ASL MRI: Impacts of arterial transit time, labeling efficiency, and hematocrit
Cerebrovascular reactivity (CVR) reflects the capacity of the brain to meet changing
physiological demands and can predict the risk of cerebrovascular diseases. CVR can be …
physiological demands and can predict the risk of cerebrovascular diseases. CVR can be …
Using arterial spin labeling to measure cerebrovascular reactivity in Moyamoya disease: Insights from simultaneous PET/MRI
Cerebrovascular reactivity (CVR) reflects the CBF change to meet different physiological
demands. The reference CVR technique is PET imaging with vasodilators but is …
demands. The reference CVR technique is PET imaging with vasodilators but is …
Conditional generative adversarial networks aided motion correction of dynamic 18F-FDG PET brain studies
LKS Sundar, D Iommi, O Muzik… - Journal of Nuclear …, 2021 - Soc Nuclear Med
This work set out to develop a motion-correction approach aided by conditional generative
adversarial network (cGAN) methodology that allows reliable, data-driven determination of …
adversarial network (cGAN) methodology that allows reliable, data-driven determination of …
Towards quantitative [18F] FDG-PET/MRI of the brain: automated MR-driven calculation of an image-derived input function for the non-invasive determination of …
LKS Sundar, O Muzik, L Rischka… - Journal of Cerebral …, 2019 - journals.sagepub.com
Absolute quantification of PET brain imaging requires the measurement of an arterial input
function (AIF), typically obtained invasively via an arterial cannulation. We present an …
function (AIF), typically obtained invasively via an arterial cannulation. We present an …
Hybrid imaging: instrumentation and data processing
State-of-the-art patient management frequently requires the use of non-invasive imaging
methods to assess the anatomy, function or molecular-biological conditions of patients or …
methods to assess the anatomy, function or molecular-biological conditions of patients or …
Predicting 15O-Water PET cerebral blood flow maps from multi-contrast MRI using a deep convolutional neural network with evaluation of training cohort bias
To improve the quality of MRI-based cerebral blood flow (CBF) measurements, a deep
convolutional neural network (dCNN) was trained to combine single-and multi-delay arterial …
convolutional neural network (dCNN) was trained to combine single-and multi-delay arterial …
Identifying Hypoperfusion in Moyamoya Disease With Arterial Spin Labeling and an [15O]-Water Positron Emission Tomography/Magnetic Resonance Imaging …
Background and Purpose—Noninvasive imaging of brain perfusion has the potential to
elucidate pathophysiological mechanisms underlying Moyamoya disease and enable …
elucidate pathophysiological mechanisms underlying Moyamoya disease and enable …