Global epidemiology and genetics of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the leading cancers worldwide. Classically, HCC
develops in genetically susceptible individuals who are exposed to risk factors, especially in …
develops in genetically susceptible individuals who are exposed to risk factors, especially in …
Imaging to predict prognosis in hepatocellular carcinoma: current and future perspectives
M Ronot, V Chernyak, A Burgoyne, J Chang, H Jiang… - Radiology, 2023 - pubs.rsna.org
The focus of hepatocellular carcinoma (HCC) research for many years has been on
noninvasive diagnosis. Standardized systematic algorithms composed of combinations of …
noninvasive diagnosis. Standardized systematic algorithms composed of combinations of …
Endoplasmic reticulum stress and autophagy in the pathogenesis of non-alcoholic fatty liver disease (NAFLD): current evidence and perspectives
CM Flessa, I Kyrou, N Nasiri-Ansari, G Kaltsas… - Current obesity …, 2021 - Springer
Abstract Purpose of Review Non-alcoholic fatty liver disease (NAFLD) is one of the most
common causes of chronic liver disease with rising prevalence worldwide. Herein, we …
common causes of chronic liver disease with rising prevalence worldwide. Herein, we …
Cholesterol metabolism: a double-edged sword in hepatocellular carcinoma
F Zhou, X Sun - Frontiers in Cell and Developmental Biology, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) represents a leading cause of cancer-related deaths
globally. The rising incidence of metabolic syndrome and its hepatic manifestation …
globally. The rising incidence of metabolic syndrome and its hepatic manifestation …
Efficacy and safety of Resmetirom, a selective thyroid hormone receptor-β agonist, in the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD …
Metabolic dysfunction-associated steatotic liver disease (MASLD) is an important public
health problem owing to its high prevalence and associated morbidity and mortality …
health problem owing to its high prevalence and associated morbidity and mortality …
The Novel GlycoPEGylated FGF21 analog pegozafermin activates human FGF receptors and improves metabolic and liver outcomes in diabetic monkeys and healthy …
M Rosenstock, L Tseng, A Pierce, E Offman… - … of Pharmacology and …, 2023 - ASPET
Pegozafermin (also known as BIO89-100) is a glycoPEGylated analog of fibroblast growth
factor 21 (FGF21) under development to treat nonalcoholic steatohepatitis (NASH) and …
factor 21 (FGF21) under development to treat nonalcoholic steatohepatitis (NASH) and …
Effect of isoquercitrin on free fatty acid-induced lipid accumulation in HepG2 cells
Liver metabolic disorders and oxidative stress are crucial factors in the development of
nonalcoholic fatty liver disease (NAFLD); however, treatment strategies to combat NAFLD …
nonalcoholic fatty liver disease (NAFLD); however, treatment strategies to combat NAFLD …
Apigenin attenuates atherosclerosis and non-alcoholic fatty liver disease through inhibition of NLRP3 inflammasome in mice
Z Lu, L Liu, S Zhao, J Zhao, S Li, M Li - Scientific Reports, 2023 - nature.com
Apigenin (APN), a flavone found in several plant foods with various biological properties
such as anti-obesity, anti-inflammation and other abilities, alleviates atherosclerosis and non …
such as anti-obesity, anti-inflammation and other abilities, alleviates atherosclerosis and non …
The advantages of physical exercise as a preventive strategy against NAFLD in postmenopausal women
E Molina‐Molina, GE Furtado, JG Jones… - European Journal of …, 2022 - Wiley Online Library
Background The prevalence and severity of nonalcoholic fatty liver disease (NAFLD)
increase in women after menopause. This narrative review discusses the causes and …
increase in women after menopause. This narrative review discusses the causes and …
Acetyl-CoA metabolism drives epigenome change and contributes to carcinogenesis risk in fatty liver disease
G Assante, S Chandrasekaran, S Ng, A Tourna… - Genome medicine, 2022 - Springer
Background The incidence of non-alcoholic fatty liver disease (NAFLD)-associated
hepatocellular carcinoma (HCC) is increasing worldwide, but the steps in precancerous …
hepatocellular carcinoma (HCC) is increasing worldwide, but the steps in precancerous …