Unconventional T cells include γδ T cells, invariant Natural Killer T cells (iNKT) cells and
Mucosal Associated Invariant T (MAIT) cells, which are distinguished from conventional T …

Autoimmune liver diseases (AILDs) include primary biliary cholangitis (PBC), primary
sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH), a family of chronic immune …

Retinoic acid, produced by intestinal dendritic cells (DCs), promotes T cell trafficking to the
intestinal mucosa by upregulating a4b7 integrin and inhibiting the generation of cutaneous …

Summary Most CD4 and CD8 T cells are restricted by conventional major histocompatibility
complex (MHC) molecules and mount TCR-dependent adaptive immune responses. In …

The newborn's immune system is faced with the challenge of having to learn quickly to fight
off infectious agents, but tolerating the colonization of the body surfaces with commensals …

The gut microbiome is a diverse microbial community composed of bacteria, viruses, and
fungi that plays a major role in human health and disease. Dysregulation of these gut …

The newborn's immune system is faced with the challenge of having to learn quickly to fight
off infectious agents, but tolerating the colonization of the body surfaces with commensals …

Gastrointestinal (GI) colonization by methicillin-resistant Staphylococcus aureus (MRSA) is
associated with a high risk of transmission and invasive disease in vulnerable populations …

Inflammatory Bowel Diseases (IBD), encompassing both Crohn's disease and ulcerative
colitis, are characterized by destruction of the gut epithelial barrier, dysbiosis and aberrant …

Resident memory T cells (Trm) are a population of long-lived T-lymphocytes which persist in
tissues and can contribute to inflammation. A small fraction can re-enter the circulation (ex …