NMR spectroscopy for metabolomics research
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …
three principal analytical techniques used in metabolomics (the other two being gas …
Accelerating metabolite identification in natural product research: toward an ideal combination of liquid chromatography–high-resolution tandem mass spectrometry …
Natural product research aims to characterize specialized metabolites from various living
organisms and assess their biological properties from either a chemical ecology or drug …
organisms and assess their biological properties from either a chemical ecology or drug …
The role of natural product chemistry in drug discovery
MS Butler - Journal of natural products, 2004 - ACS Publications
Although traditionally natural products have played an important role in drug discovery, in
the past few years most Big Pharma companies have either terminated or considerably …
the past few years most Big Pharma companies have either terminated or considerably …
Metabolomics: current analytical platforms and methodologies
During the previous decade, a new array of analytical methodologies and technologies were
introduced related to the analysis of microbial, plant and animal metabolomes (complete …
introduced related to the analysis of microbial, plant and animal metabolomes (complete …
Beyond the paradigm: Combining mass spectrometry and nuclear magnetic resonance for metabolomics
DD Marshall, R Powers - Progress in nuclear magnetic resonance …, 2017 - Elsevier
Metabolomics is undergoing tremendous growth and is being employed to solve a diversity
of biological problems from environmental issues to the identification of biomarkers for …
of biological problems from environmental issues to the identification of biomarkers for …
Advances in structure elucidation of small molecules using mass spectrometry
The structural elucidation of small molecules using mass spectrometry plays an important
role in modern life sciences and bioanalytical approaches. This review covers different soft …
role in modern life sciences and bioanalytical approaches. This review covers different soft …
Understanding glycaemic control and current approaches for screening antidiabetic natural products from evidence-based medicinal plants
Abstract Type 2 Diabetes Mellitus has reached epidemic proportions as a result of over-
nutrition and increasingly sedentary lifestyles. Current therapies, although effective, are not …
nutrition and increasingly sedentary lifestyles. Current therapies, although effective, are not …
Plant-derived compounds in clinical trials
Plants remain an important source of new drugs, new drug leads and new chemical entities.
The plant-based drug discovery resulted mainly in the development of anticancer and anti …
The plant-based drug discovery resulted mainly in the development of anticancer and anti …
Combined nuclear magnetic resonance spectroscopy and mass spectrometry approaches for metabolomics
MPM Letertre, G Dervilly, P Giraudeau - Analytical chemistry, 2020 - ACS Publications
Metabolomics is based on cutting-edge analytical methods that provide a “snapshot” of all
the detectable metabolites, small molecules generally weighing under 1200 Da, present in …
the detectable metabolites, small molecules generally weighing under 1200 Da, present in …
Cryogenically cooled probes—a leap in NMR technology
H Kovacs, D Moskau, M Spraul - Progress in Nuclear Magnetic Resonance …, 2005 - Elsevier
During the 50 years of NMR, the technology has renewed itself again and again although
the basic physical principles remain the same. As technical advances and novel materials …
the basic physical principles remain the same. As technical advances and novel materials …