Genetic restrictive cardiomyopathy: causes and consequences—an integrative approach
D Cimiotti, H Budde, R Hassoun, K Jaquet - International Journal of …, 2021 - mdpi.com
The sarcomere as the smallest contractile unit is prone to alterations in its functional,
structural and associated proteins. Sarcomeric dysfunction leads to heart failure or …
structural and associated proteins. Sarcomeric dysfunction leads to heart failure or …
Nicotinamide for the treatment of heart failure with preserved ejection fraction
M Abdellatif, V Trummer-Herbst, F Koser… - Science translational …, 2021 - science.org
Heart failure with preserved ejection fraction (HFpEF) is a highly prevalent and intractable
form of cardiac decompensation commonly associated with diastolic dysfunction. Here, we …
form of cardiac decompensation commonly associated with diastolic dysfunction. Here, we …
Protein hydrogels: the Swiss army knife for enhanced mechanical and bioactive properties of biomaterials
C Huerta-López, J Alegre-Cebollada - Nanomaterials, 2021 - mdpi.com
Biomaterials are dynamic tools with many applications: from the primitive use of bone and
wood in the replacement of lost limbs and body parts, to the refined involvement of smart …
wood in the replacement of lost limbs and body parts, to the refined involvement of smart …
Beyond gene-disease validity: capturing structured data on inheritance, allelic requirement, disease-relevant variant classes, and disease mechanism for inherited …
KS Josephs, AM Roberts, P Theotokis, R Walsh… - Genome medicine, 2023 - Springer
Background As the availability of genomic testing grows, variant interpretation will
increasingly be performed by genomic generalists, rather than domain-specific experts …
increasingly be performed by genomic generalists, rather than domain-specific experts …
Exploring TTN variants as genetic insights into cardiomyopathy pathogenesis and potential emerging clues to molecular mechanisms in cardiomyopathies
The giant protein titin (TTN) is a sarcomeric protein that forms the myofibrillar backbone for
the components of the contractile machinery which plays a crucial role in muscle disorders …
the components of the contractile machinery which plays a crucial role in muscle disorders …
Protein Hydrogels: The Swiss Army Knife for Enhanced Mechanical and Bioactive Properties of Biomaterials. Nanomaterials 2021, 11, 1656
C Huerta-López, J Alegre-Cebollada - 2021 - search.proquest.com
Biomaterials are dynamic tools with many applications: from the primitive use of bone and
wood in the replacement of lost limbs and body parts, to the refined involvement of smart …
wood in the replacement of lost limbs and body parts, to the refined involvement of smart …