[HTML][HTML] Membrane-attached mammalian cytochromes P450: An overview of the membrane's effects on structure, drug binding, and interactions with redox partners
Mammalian cytochromes P450 are an important class of enzymes involved in the
biotransformation of many endo-and exogenous compounds. Cytochrome P450 isoforms …
biotransformation of many endo-and exogenous compounds. Cytochrome P450 isoforms …
Cytochrome P450 monooxygenase systems: Diversity and plasticity for adaptive stress response
IM Mokhosoev, DV Astakhov, AA Terentiev… - Progress in Biophysics …, 2024 - Elsevier
Superfamily of cytochromes P450 (CYPs) is composed of heme-thiolate-containing
monooxygenase enzymes, which play crucial roles in the biosynthesis, bioactivation, and …
monooxygenase enzymes, which play crucial roles in the biosynthesis, bioactivation, and …
Local Electric Fields Drives the Proton-Coupled Electron Transfer within Cytochrome P450 Reductase
Cytochrome P450 enzymes play a pivotal role in biosynthetic and metabolic transformations.
Especially, cytochrome P450 reductase (CPR) acts as the key electron donor for the oxygen …
Especially, cytochrome P450 reductase (CPR) acts as the key electron donor for the oxygen …
Roles of Ferredoxin-NADP+ Oxidoreductase and Flavodoxin in NAD(P)H-Dependent Electron Transfer Systems
T Iyanagi - Antioxidants, 2022 - mdpi.com
Distinct isoforms of FAD-containing ferredoxin-NADP+ oxidoreductase (FNR) and ferredoxin
(Fd) are involved in photosynthetic and non-photosynthetic electron transfer systems. The …
(Fd) are involved in photosynthetic and non-photosynthetic electron transfer systems. The …
[HTML][HTML] Molecular mechanism of metabolic NAD (P) H-dependent electron-transfer systems: The role of redox cofactors
T Iyanagi - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2019 - Elsevier
Abstract NAD (P) H-dependent electron-transfer (ET) systems require three functional
components: a flavin-containing NAD (P) H-dehydrogenase, one-electron carrier and metal …
components: a flavin-containing NAD (P) H-dehydrogenase, one-electron carrier and metal …
The role of the FMN-domain of human cytochrome P450 oxidoreductase in its promiscuous interactions with structurally diverse redox partners
NADPH cytochrome P450 oxidoreductase (CPR) is the obligatory electron supplier that
sustains the activity of microsomal cytochrome P450 (CYP) enzymes. The variant nature of …
sustains the activity of microsomal cytochrome P450 (CYP) enzymes. The variant nature of …
A minimal functional complex of cytochrome P450 and FBD of cytochrome P450 reductase in nanodiscs
Structural interactions that enable electron transfer to cytochrome‐P450 (CYP450) from its
redox partner CYP450‐reductase (CPR) are a vital prerequisite for its catalytic mechanism …
redox partner CYP450‐reductase (CPR) are a vital prerequisite for its catalytic mechanism …
Functional and structural insight into the flexibility of cytochrome P450 reductases from Sorghum bicolor and its implications for lignin composition
Plant NADPH-dependent cytochrome P450 reductase (CPR) is a multidomain enzyme that
donates electrons for hydroxylation reactions catalyzed by class II cytochrome P450 …
donates electrons for hydroxylation reactions catalyzed by class II cytochrome P450 …
Structure of the Arabidopsis thaliana NADPH‐cytochrome P450 reductase 2 (ATR2) provides insight into its function
Members of the cytochrome P450 family catalyze a variety of mono‐oxygenase reactions,
and for the eukaryotic membrane‐bound members, NADPH is typically used as the reducing …
and for the eukaryotic membrane‐bound members, NADPH is typically used as the reducing …
Integration of transcriptomic and metabolomic analysis of the mechanism of dietary N-carbamoylglutamate in promoting follicle development in yaks
J Zhou, S Yue, J Du, B Xue, L Wang, Q Peng… - Frontiers in Veterinary …, 2022 - frontiersin.org
Yak is the main livestock in the highlands of China. The low reproductive rate of yaks is a
serious constraint on their production and utility. N-carbamylglutamate (NCG) can increase …
serious constraint on their production and utility. N-carbamylglutamate (NCG) can increase …